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Research Associate (Fixed Term)

University of Cambridge - Department of Medicine

Location: Cambridge
Salary: £33,309 to £40,927
Hours: Full Time
Contract Type: Fixed-Term/Contract
Placed On: 5th August 2022
Closes: 17th August 2022
Job Ref: RC32579

Long-term infectious and inflammatory conditions are a complex host-pathogen response that is poorly understood because of the multiple physical and biological factors that are involved. This project will study chronic rhinosinusitis (CRS) which is a common, but relatively intractable clinical problem. In this project we will refine our established bacterial infection - respiratory models (epithelial air-liquid interface models, organ on a chip devices) to characterise the epithelial immune responses to bacteria. Using the information from this analysis we will develop a simplified minimal inflammatory model to determine changes in the physical properties of epithelial responses and whether these can be modified to develop new treatments for intractable sinus infections.  This work is part of an interdisciplinary project run by a team of biological, medical, physical and mathematical scientists to maximise the potential of gaining novel insights at the life sciences/physics interface and to generate new therapeutic approaches.

We are looking for a scientist with broad experience in working with in vitro respiratory infection models, particularly with bacterial pathogens, to join our research team. We particularly welcome applicants who are interested in learning cutting edge microfluidics techniques.  We hope to recruit a colleague who shares our passion for discovery and who looks for an exciting challenge within our highly multidisciplinary group.

Our lab is located in the Department of Medicine integrated into the new Heart and Lung Research Institute, the Cambridge Institute of Therapeutic Immunology and Infectious Disease (CITIID), for more info, see https://www.citiid.cam.ac.uk and https://www.infectiousdisease.cam.ac.uk/directory/ceb27%40cam.ac.uk

Our research is funded by the EPSRC, BBSRC, Wellcome Trust, the MRC, the Dementia Research Institute, Janssen, Astex and Alzheimer's Research UK. We have extensive collaborations on and off campus.

For informal inquiries please contact Professor Clare Bryant (ceb27@cam.ac.uk

Fixed-term: The funds for this post are available for 2 years in the first instance.

Interview Date: To be confirmed

To apply online for this vacancy and to view further information about the role, please visit:

http://www.jobs.cam.ac.uk/job/36363.

Please ensure that you upload a covering letter and CV in the Upload section of the online application. The covering letter should outline how you match the criteria for the post and why you are applying for this role. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application.

Please include details of your referees, including email address and phone number, one of which must be your most recent line manager.

Please quote reference RC32579 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

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