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PhD Studentship - Avian iPSCs and Cerebral Organoids (Fixed Term)

University of Cambridge - Department of Physiology, Development and Neuroscience

Qualification Type: PhD
Location: Cambridge
Funding for: UK Students, EU Students, International Students
Funding amount: Funded for three years and will cover home fees
Hours: Full Time
Placed On: 21st September 2022
Closes: 1st December 2022
Reference: PM33258

Department/Location: Department of Physiology, Development and Neuroscience

Supervisors: Prof. David Keays (LMU Munich/Cambridge) and Dr. Madeline Lancaster (LMB, Cambridge)

The Project - An opportunity exists for a driven and passionate student to undertake a Phd under the supervision of Prof. David Keays and Dr Madeline Lancaster on avian stem cells and cerebral organoids. This joint project will exploit the Keays lab's expertise in Avian biology and the Lancaster Lab's experience in self organising neural tissue. The project will aim to generate a library of avian iPSCs and ES cells for the generation of three dimensional neuronal cultures. The latter will then be employed to interrogate Avian specific aspects of neurodevelopment and sensory biology exploiting CRISP-Cas9 genome editing, single cell sequencing, and histological methods. 

The ideal candidate - This ambitious project requires a candidate with an existing interest in stem cell biology and/or developmental neuroscience. They should be patient, be impervious to scientific failure, value quantitative approaches and have a strong academic record. Prior experience in cell culture methods and molecular biology will be advantageous. The student will be based in the Physiology, Development and Neuroscience department (PDN) in Cambridge, but should be prepared to spend time at the Laboratory of Molecular Biology (LMB) in Cambridge and at LMU in Munich. We actively encourage applications from prospective postgraduate students from underrepresented groups. The position is funded for three years and will cover home fees, as well as costs associated with travel, training and consumables.

Website: www.Keayslab.org and www2.mrc-lmb.cam.ac.uk/groups/lancaster/ 

Application: Please send applications to dak55@cam.ac.uk and mlancast@mrc-lmb.cam.ac.uk. Please include a CV, letter of motivation and the contact details of two referees. The deadline for applications is December 1st 2022, but interested applicants are encourage to contact us beforehand. It is anticipated that the student would begin in the Easter Term in 2023 (April 17th). 

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

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