Postdoc in Computational Immunology Domínguez Conde Group Population and Medical Genomics Programme

Human Technopole (HT) is a new interdisciplinary life science research institute, created and supported by the Italian government, with the aim of developing innovative strategies to improve human health. 

The position of Postdoctoral Fellow position at the Domínguez Conde group aims to investigate mechanisms of gene regulation in the developing immune system using a range of single-cell cytometry and genomic technologies. We are seeking a highly motivated and self-driven individual to join us in our quest to improve the molecular understanding of human immune development in health and disease.

The successful candidate will report directly to Cecilia Domínguez Conde, Group Leader at the Centre for Genomics.

(S)He will have the following main responsibilities:

• Analysis and interpretation of multimodal single-cell sequencing datasets (including scRNA-seq, scATAC-seq and CITE-seq)
• Design of new approaches to integrate and query existing and newly generated single-cell datasets
• Implement/develop novel analytical methods to infer differentiation trajectories and gene regulatory networks (GRN) during human immune development
• Analysis of the clonal structure of developing immune cells via single-cell profiling of antigen receptor sequences
• Assessment of trajectory or GRN disruption in inborn errors of immunity
• Proactive interaction with the Genome Analysis Unit and the Genomics Facility for data generation and analysis

Essential:

• PhD degree in immunology, genomics or bioinformatics
• Strong track record of previous research projects
• Experience with high-throughput sequencing data
• Fluency in English – HT is an international research institute

Required personal skills:

• Strong interpersonal skills such as negotiating, problem-solving, and knowledge-sharing
• Ability to independently set priorities and meet deadlines
• Ability to work in a multi-cultural environment with sensitivity and respect for diversity

Special consideration will be given to candidates who are part of the protected categories list, according to L. 68/99

Application Instructions:

• CV 
• A  motivation letter in English explaining your reasons to apply for this position
• Names and contacts of 2 referees

For specific enquires concerning the role only, please contact cecilia.dominguez_@recruitee.com (this email address should not be used to send applications).

Additional information

HT offers a highly collaborative, international culture to foster top quality, interdisciplinary research by promoting a vibrant environment consisting of independent research groups with access to outstanding graduate students, postdoctoral fellows and core facilities.

HT is an inclusive employer that fosters diversity and engages systematically to ensure that equal employment opportunities are provided without regard to age, race, creed, religion, sex, disability, medical condition, sexual orientation, gender identity or expression, national or ethnic origin or any other legally recognized status entitled to protection under applicable laws.
HT offers attractive conditions and benefits appropriate to a leading, internationally competitive, research organization that promotes a collegial and open atmosphere. The compensation package granted will be internationally competitive and comprise pension scheme, medical and other social benefits and support for relocation and installation. Candidates coming to Italy for the first time, or returning after residing abroad, benefit from very attractive income tax benefits.