Back to search results
Header Image

Research Technician: Systems Genetics

European Molecular Biology Laboratory (EMBL)

Contract Duration-Length of Time (years/months):

3 year

About the team/job

The research group of Lars Steinmetz is seeking an outstanding, ambitious, and independently working research technician. Our group develops and applies genome-wide technologies to elucidate the genetic basis of complex phenotypes, the functions and mechanisms of transcription, and the genetic and molecular systems underlying diseases. The group works in an interdisciplinary manner across diverse projects, integrating experimental and computational biology. 

Your role

The Research Technician’s responsibilities will include:

  • Develop CRISPR/Cas9 tools to perturb cell culture models including cardiomyocytes and immune cells, as well as mice.
  • Handling of human cell model systems, generation of stable cell lines, transfections, lentiviral transductions, flow cytometry, and microscopy.
  • Basic molecular biology techniques, including molecular cloning, DNA/RNA preparation and analysis, generation of CRISPR/Cas9 libraries for genetic screens.
  • Performing functional genomics screens and using cutting-edge single-cell sequencing technologies to characterize the effects of CRISPR perturbations.
  • Testing, developing and evaluation of new experimental protocols, in particular in the field of next generation sequencing (RNA-seq, single-cell sequencing, NGS library preparations).
  • The Research Technician will contribute to scientific projects at all stages, ranging from experimental design to manuscript preparation.
  • Working together with 1-2 dedicated senior members in the lab, as well as the EMBL Genomics Core Facility.
  • Training new group members and visitors in technologies and protocols used in the laboratory. Oversee supplies and equipment in the lab, routine administrative support. 

You have

Applicants should have an appropriate University degree (PhD, BSc or MSc degree) and a minimum of 1 year practical experience. The successful candidate will be familiar with the biological mechanisms underlying gene expression. (S)he will have extensive hands-on experience in human cell culture model systems including handling of cells and CRISPR/Cas9 genome engineering. Experience in iPSCs is highly desirable. Additional experience in high throughput technologies and expertise in next generation sequencing and FACS techniques would be a benefit. The appointed candidate will demonstrate a high degree of motivation, be self-driven and capable of working independently, but also enjoy being part of an interdisciplinary team of scientists in a highly collaborative international working atmosphere. We expect the willingness to learn and develop to gain new knowledge and skills, and to contribute to the completion of project goals. We expect the successful candidate to be well organized, with an attention to detail and record-keeping. Excellent communication skills and fluency in written and verbal English are essential. 

Why join us

This is a fantastic opportunity to work in a team at the cutting edge of technology development in a very exciting area at a world leading institute. EMBL, Europe’s flagship laboratory for the life sciences, is an intergovernmental research institute with more than 80 independent research groups across six sites in Europe. We are an inclusive, equal opportunity employer offering attractive conditions and benefits appropriate to an international research organization with a very collegial and family friendly working environment. The remuneration package comprises a competitive salary, a comprehensive pension scheme, medical, educational and other social benefits. The Steinmetz Lab works across two sites at EMBL Heidelberg and Stanford University and is one of the world’s leading labs in technology development for functional genomics, by combining experimental work and bioinformatics. 

Location: Heidelberg - Germany
Salary: Grade 4 - 6
Hours: Full Time
Contract Type: Fixed-Term/Contract
Placed On: 29th November 2022
Closes: 10th January 2023
Job Ref: HD02319
 
   
We value your feedback on the quality of our adverts. If you have a comment to make about the overall quality of this advert, or its categorisation then please send us your feedback
Show all jobs for European Molecular Biology Laboratory (EMBL) …
Advert information

Type / Role:

Subject Area(s):

Location(s):

* Salary has been converted at the prevailing rate on the date placed
Job tools
 

PhD Alert Created

Job Alert Created

Your PhD alert has been successfully created for this search.

Your job alert has been successfully created for this search.

Ok Ok

PhD Alert Created

Job Alert Created

Your PhD alert has been successfully created for this search.

Your job alert has been successfully created for this search.

Manage your job alerts Manage your job alerts

Account Verification Missing

In order to create multiple job alerts, you must first verify your email address to complete your account creation

Request verification email Request verification email

jobs.ac.uk Account Required

In order to create multiple alerts, you must create a jobs.ac.uk jobseeker account

Create Account Create Account

Alert Creation Failed

Unfortunately, your account is currently blocked. Please login to unblock your account.

Email Address Blocked

We received a delivery failure message when attempting to send you an email and therefore your email address has been blocked. You will not receive job alerts until your email address is unblocked. To do so, please choose from one of the two options below.

Max Alerts Reached

A maximum of 5 Job Alerts can be created against your account. Please remove an existing alert in order to create this new Job Alert

Manage your job alerts Manage your job alerts

Creation Failed

Unfortunately, your alert was not created at this time. Please try again.

Ok Ok

Create PhD Alert

Create Job Alert

When you create this PhD alert we will email you a selection of PhDs matching your criteria.When you create this job alert we will email you a selection of jobs matching your criteria. Our Terms and Conditions and Privacy Policy apply to this service. Any personal data you provide in setting up this alert is processed in accordance with our Privacy Notice

Create PhD Alert

Create Job Alert

When you create this PhD alert we will email you a selection of PhDs matching your criteria.When you create this job alert we will email you a selection of jobs matching your criteria. Our Terms and Conditions and Privacy Policy apply to this service. Any personal data you provide in setting up this alert is processed in accordance with our Privacy Notice

 
 

Browser Upgrade Recommended

jobs.ac.uk has been optimised for the latest browsers.

For the best user experience, we recommend viewing jobs.ac.uk on one of the following:

Google Chrome Firefox Microsoft Edge