Molecular Biologist

Harwell Campus, Oxfordshire

Fixed Term until Until 31 March 2027

Closing date for application 05-Feb-2023 

About Us

The Mary Lyon Centre at MRC Harwell (MLC) https://www.har.mrc.ac.uk/  is located on the Harwell Campus, a thriving science hub specialising in technologies in the fields of health, space and energy.  We focus on preclinical research using mouse models, which supports clinical research and therapy discovery. The MRC is an excellent place to develop yourself further and a range of training & development opportunities will be available to you, including professional registration with the Science Council.

The Mary Lyon Centre (MLC) at the Medical Research Council Harwell Institute requires a skilled molecular biologist to reinforce a busy service that provides support to the UK research community with mouse genome engineering, expression studies and analysis of genetically altered mouse embryos.

The MCB group at the MLC undertakes generation and quality control of a broad range of targeted alleles as a bespoke service for individual laboratories. The group requires a research specialist in Molecular Biology to provide capacity to evolve and implement complex genome engineering production and validation processes. The post-holder will also provide support for both the design and the analysis of mouse genetic alterations. The post-holder will be based in the Molecular and Cellular Biology group and will coordinate some genome engineering projects and functional analysis studies in in vitro models and/or mouse adult and embryonic tissues. They will work in a twelve-strong team under the guidance of the Molecular and Cellular Biology Deputy Manager

About you

• PhD in Biomedical Sciences (plant or microbiology specialists need not apply), or MSc with a strong track record of relevant molecular biology work
• Previous work with genetically modified animal materials
• Previous experience in genotyping of genetically edited materials
• Design and implementation of gene targeting and/or genome editing strategies
• Previous experience with Sanger sequencing DNA sequence analysis software
• Experience of delivery of scientific projects
• Experience of basic molecular biology techniques, including PCR, qPCR, Southern or western blotting
• Experience of methods employed for mouse genome engineering 

Benefits:

Choosing to come to work at the MRC (part of UK Research and Innovation (UKRI)) means that you will have access to a whole host of benefits, from a defined-benefit pension scheme and excellent holiday entitlement, to access to employee shopping/travel discounts and a salary sacrifice cycle-to-work scheme.  In addition, you will have the opportunity to contribute to the work of a world-class medical research organisation.

The MRC values the diverse skills and experience of its employees and is committed to achieving equality of treatment for all. Our objectives are that all individuals shall have equal opportunities for employment and advancement on the basis of their skills, aptitudes and abilities.

How to Apply

For full details and to apply: https://mrc.tal.net/vx/lang-en-GB/appcentre-1/candidate/postings/2208

Please quote reference MLC 2036, upload your CV along with a covering letter stating why you are applying for this role (providing evidence against the requirements of the job as per the job description and person specification

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