Back to search results

Postdoctoral Researcher in Translational Research Immunology

University of Oxford - Nuffield Department of Surgical Sciences

Location: Oxford
Salary: £34,308 to £42,155 per annum. Grade 7
Hours: Full Time
Contract Type: Fixed-Term/Contract
Placed On: 25th January 2023
Closes: 13th February 2023
Job Ref: 163096

Nuffield Department of Surgical Sciences, John Radcliffe Hospital, Headington, Oxford, OX3 9DU

Contract type: Fixed term for 12 months

About the role

You will work on a new, translational project, funded by the MRC Confidence in Concept fund and industry partner, Oxford Biomedica, to generate antigen-specific, human regulatory B cells (Breg). You will be responsible for the development and implementation of lentiviral platforms and CRISPR/Cas9 techniques to deliver genes encoding B cell receptor constructs to primary human B cells. Successful realisation of this project will demonstrate proof of concept design of precision B cell therapies in transplantation and immune-mediated disorders. You will be based within the Nuffield Department of Surgical Sciences in the John Radcliffe Hospital, as your normal place of work. 

This position offers a unique opportunity to contribute to the work of an internationally recognised team of scientists and clinicians within the Translational Research Immunology Group (TRIG). TRIG has extensive experience in studying and translating regulatory cell therapy from the bench to the bedside as new treatments for transplant recipients. Breg have been shown to have key roles in defining outcomes in organ transplantation and autoimmune disease. TRIG has developed new methods of expanding human Breg in vitro, to enable in depth study and therapeutic development. 

About you

You will hold a PhD (or be near to completion: thesis submitted) in a relevant area such as cellular or molecular biology at the time of application. Experience with genetic editing techniques such as vector manufacture, viral transfection, PCR and sequencing is desirable but not essential. You will have demonstrated the ability to work independently within projects, with the ability to communicate results clearly and succinctly in presentations, manuscripts and grant applications.   

This position is available from February 2023, fixed-term for 12 months and is funded by the Medical Research Council Confidence in Concept & Oxford Biomedica. 

Application Process

If you would like to discuss this role, please contact the Human Resources team on recruitment@nds.ox.ac.uk.

Applications for this vacancy are to be made online. You will be required to upload a supporting statement, setting out how you meet the selection criteria, curriculum vitae and the names and contact details of two referees as part of your online application. Please quote reference NDSA876B on all correspondence.

Only applications received before noon on Monday 13 February 2023 can be considered.

Interviews will be held weeks commencing Thursday 23 February 2023.

Committed to equality and valuing diversity

We value your feedback on the quality of our adverts. If you have a comment to make about the overall quality of this advert, or its categorisation then please send us your feedback
Advert information

Type / Role:

Subject Area(s):

Location(s):

Job tools
 

PhD Alert Created

Job Alert Created

Your PhD alert has been successfully created for this search.

Your job alert has been successfully created for this search.

Ok Ok

PhD Alert Created

Job Alert Created

Your PhD alert has been successfully created for this search.

Your job alert has been successfully created for this search.

Manage your job alerts Manage your job alerts

Account Verification Missing

In order to create multiple job alerts, you must first verify your email address to complete your account creation

Request verification email Request verification email

jobs.ac.uk Account Required

In order to create multiple alerts, you must create a jobs.ac.uk jobseeker account

Create Account Create Account

Alert Creation Failed

Unfortunately, your account is currently blocked. Please login to unblock your account.

Email Address Blocked

We received a delivery failure message when attempting to send you an email and therefore your email address has been blocked. You will not receive job alerts until your email address is unblocked. To do so, please choose from one of the two options below.

Max Alerts Reached

A maximum of 5 Job Alerts can be created against your account. Please remove an existing alert in order to create this new Job Alert

Manage your job alerts Manage your job alerts

Creation Failed

Unfortunately, your alert was not created at this time. Please try again.

Ok Ok

Create PhD Alert

Create Job Alert

When you create this PhD alert we will email you a selection of PhDs matching your criteria.When you create this job alert we will email you a selection of jobs matching your criteria. Our Terms and Conditions and Privacy Policy apply to this service. Any personal data you provide in setting up this alert is processed in accordance with our Privacy Notice

Create PhD Alert

Create Job Alert

When you create this PhD alert we will email you a selection of PhDs matching your criteria.When you create this job alert we will email you a selection of jobs matching your criteria. Our Terms and Conditions and Privacy Policy apply to this service. Any personal data you provide in setting up this alert is processed in accordance with our Privacy Notice

 
 
More jobs from University of Oxford

Show all jobs for this employer …

More jobs like this
Join in and follow us

Browser Upgrade Recommended

jobs.ac.uk has been optimised for the latest browsers.

For the best user experience, we recommend viewing jobs.ac.uk on one of the following:

Google Chrome Firefox Microsoft Edge