|Location:||Newcastle upon Tyne|
|Funding for:||UK Students, EU Students, International Students|
|Placed On:||10th March 2023|
|Closes:||14th May 2023|
100% of home tuition fees paid and an annual stipend (living expenses) of £17,668. Successful international candidates will be required to fund the difference between the home fees and international fees.
Primary liver cancer is the 3rd leading cause of cancer related deaths worldwide and current immunotherapies are only effective in a quarter of patients. Understanding why some patients respond and others do not is a key unanswered question in the cancer field.
Previous work in the group has shown that immunotherapy resistance in liver cancer is associated with fibrosis and cancer associated fibroblast activation. In this exciting project the student will build on this work and aim to understand the role of cancer associated fibroblasts in liver cancer progression and determine whether they can be targeted therapeutically to improve immunotherapy responses.
The student will join a highly motivated team of researchers in the Newcastle Fibrosis Research Group, committed to delivering high-quality translational research in chronic disease and cancer. Throughout the project the student will receive high quality training in experimental design, data analysis and interpretation as well as develop skills in experimental disease modelling, including pre-clinical mouse models, immunology, metabolism and cell signalling. The student will be encouraged to attend scientific meetings to develop their scientific knowledge and communication skills.
This project is expected to discover new roles of cancer associated fibroblasts in liver cancer immunotherapy responses and lead to the identification of novel treatment strategies.
Number Of Awards
3 year PhD
Dr Jack Leslie - Biosciences Institute, Newcastle University
Dr Shoba Amarnath - Biosciences Institute, Newcastle University
You must have, or expect to achieve, at least a 2:1 honours degree or international equivalent, in an appropriate subject, including: biomedical sciences, bioinformatics. A further qualification such as an MRes is advantageous.
This award is available to home and international applicants. Successful international candidates will be required to make up the difference between the home fees and international fees.
Successful EU applicants will be considered for the Vice-Chancellor’s EU Research Scholarship.
English Language requirements: IELTS 6.5 overall, with 5.5 or more in each sub-skill.
How To Apply
You must apply through the University’s Apply to Newcastle Portal.
In the ‘Course choice’ tab:
You will then need to provide the following information in the ‘Further Details’ section:
For further details, please contact:
Dr Jack Leslie
Type / Role: