Location: | Birmingham |
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Salary: | £33,348 to £43,155 with potential progression once in post to £45,737 |
Hours: | Full Time |
Contract Type: | Fixed-Term/Contract |
Placed On: | 22nd March 2023 |
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Closes: | 30th April 2023 |
Job Ref: | 100570 |
Fixed Term contract up to 3 years
Role/Project Background
The research group studies the functional mechanisms of proteins, nucleic acids and their complexes by integrative structural biology. The laboratory uses and develops high-field NMR spectroscopy methods as major structural biology tool, in combination with several other techniques. The Research Fellow will work in one of the following areas: RNA metabolism, regulation of gene expression, DNA repair or signalling. The post holder will use NMR spectroscopy, X-ray crystallography and/or Electron Microscopy, as well as Mass Spectrometry and Small Angle Scattering, to study the structure of protein–protein or protein–nucleic acids complexes and discover the principles of their function and regulation. There are opportunities to develop new approaches to integrative structural biology with the combination of the techniques mentioned above. In addition, the RF will use molecular and cellular biology, biophysical and biochemical techniques to test the activity and study mechanisms of biomolecular complexes in vitro and in vivo.
We are a group of highly motivated structural biologists with an interdisciplinary, international background. We offer a first-class research environment with state-of-the-art equipment in molecular biology and biochemistry and the best equipped biomolecular NMR facility in the UK (comprising 1000, 900 and 800 MHz spectrometers equipped with cryoprobes and MAS probes for both solution- and solid-state NMR spectroscopy). Excellent EM instrumentation is available at the Midlands Regional Cryo Electron Microscope Facility in Leicester.
Main duties
Person Specification
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Valuing excellence, sustaining investment
We value diversity and inclusion at the University of Birmingham and welcome applications from all sections of the community and are open to discussions around all forms of flexible working
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