Postdoctoral Training Fellow - Peptide Inhibitors of Cell Cycle Interactions (ID 562)

SUMMARY OF THE POST              

We are recruiting a highly motivated team member to the Short Linear Motif Team in the Division of Cancer Biology. A Cancer Research UK-funded Postdoctoral Training Fellow position (on a fixed-term contract for 2 1/2 years in the first instance) will be available to develop and apply therapeutic target discovery methods focussing on the inhibition of interactions in the cell cycle. This work is part of a larger project characterising motif-mediated interactions to identify weak points in cancer cells for therapeutic intervention.

SPECIFIC DUTIES AND RESPONSIBILITIES

• To design and undertake experiments appropriate for the project, working in a semi-independent fashion involving the following:
  • Develop and apply methods to create polypeptides targeting motif-binding pockets
  • Develop and optimise methods to discover therapeutic targets using peptide inhibitors
  • Apply these methods in a medium-throughput manner to identify and characterise novel therapeutic targets
  • Interpret findings and plan future experiments.
  • Maintain accurate records of experiments and data.
• To coordinate with other members of the team and the Division and contribute to a multidisciplinary collaboration by providing scientific input into a developing research project.
• To contribute to the academic life of the laboratory, and by extension of the ICR.
• To further develop a knowledge of the literature in the subject area.
• Presentation of seminars and journal clubs.
• Publish articles describing these novel methodologies and analyses
• Be familiar with ICR’s approach towards risk management, including its policies and procedures, which require all staff to play an active part in identifying and managing risk.

Any other duties which may be required and are consistent with the nature and grade of the post.

This job description is a reflection of the present position and is subject to review and alteration in detail and emphasis in the light of future changes or development.

The ICR has a workforce agreement stating that Postdoctoral Training Fellows can only be employed for up  to 7 years as PDTF at the ICR, providing total postdoctoral experience (including previous employment at this level elsewhere) does not exceed 10 years

Department/Directorate Information:

The recruited PDTF will join the Short Linear Motif Team in the Division of Cancer Biology

Further Details

For further informal inquiries about the position, contact Dr. Norman Davey (norman.davey@icr.ac.uk) with the email title “Recruitment - Postdoctoral Fellow - Peptide Inhibitors of Cell Cycle Interactions”. Please do not submit your formal application by email, applications must be submitted on the ICR Careers portal. Please complete the application form and include the following:

• A 1-page letter explaining your research background, research interests, key skills in relation to the position and motivation for applying.
• A curriculum vitae including a list of peer-reviewed publications (may include papers under review).
• Contact details for 2 former supervisors 

We look forward to receiving applications from all candidates, wherever in the world they are currently based. We will select those who display the potential to become, or to support, the world leading cancer researchers of the future based on their application and performance at interview. However, we particularly welcome British applicants from black and ethnic minority backgrounds, as they are under-represented within the ICR and nationwide in STEM roles.

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