Experimental Officer in Computational Metabolomics

Location: University of Birmingham, Edgbaston, Birmingham UK 

Work schedule is 5 days per week including weekends  

Grade 7

Full Time/Fixed Term contract up to July 2025 

Summary of role: 

The post has been created by a collaboration between the Phenome Centre Birmingham and the new EU H2020 PrecisionTox consortium (https://www.birmingham.ac.uk/research/centre-for-precision-toxicology/index.aspx ). The post holder will be primarily involved in the application of computational metabolomics to process, annotate and analyse the world's largest comparative, multi-omics toxicological dataset generated as part of PrecisionTox. 

The bioinformatics post will be part of the Phenome Centre Birmingham (PCB) team and contribute to fulfilling the research objectives of the centre with a focus on the development, implementation and application of computational approaches for metabolic phenotyping in human health and toxicology. 

The role will primarily include the development, implementation and application of data processing workflows, including experimental design, pre-processing, and statistical analysis of large scale LC-MS based metabolomics studies; collaboration with researchers within and external to the university (academic, industry, scientific instrument manufacturers); and providing training and support in bioinformatics. 

Main Duties and Responsibilities:

• Develop and implement computational workflows, to be applied in human health and toxicology research, enhancing the capabilities and capacity of the PCB
• Perform extensive pre-processing of metabolomics data acquired on the mass spectrometry platforms in the PCB, in particular for the PrecisionTox project
• Conduct an array of univariate and multivariate statistical analysis of data acquired on the mass spectrometry platforms, in particular for the PrecisionTox project
• Manage and ensure optimal operation of software and other bioinformatics resources so to meet research goals in a timely manner
• Curate datasets both locally at Birmingham and at international data repositories 

We are looking for someone with: 

• First degree in bioinformatics, (bio)chemistry, mathematics, statistics or computer science, and a PhD or equivalent experience in computational metabolomics, chemoinformatics, bioinformatics, biostatistics or a closely related area
• High level of experience in the computational analysis of metabolomics data.
• High level analytical capability.
• Good understanding of principles involved in data processing, including relevant software (e.g. XCMS, Compound Discoverer, etc)
• Hands-on skills in bioinformatics, data science or data analytics. 

The closing date for applications is DATE. 

For further information please contact Dr Ralf Weber, r.j.weber@bham.ac.uk 

We value diversity at The University of Birmingham  and welcome applications from all sections of the community

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