23P-53 Bioinformatician/Senior Bioinformatician (Band D/E)

Organisation position and purpose

We are looking for a bioinformatician to join the core Bioinformatics facility of the Pirbright Institute. This post is a permanent position incorporating a service component as well as opportunities for research. The Institute has excellent livestock containment facilities and well-tuned core facilities (sequencing, microscopy and flow cytometry) producing unique datasets.

This post will report to the head of Computational Biology. There are three components to the position: 50% sequencing-based core bioinformatics, 25% research with Genomics and Computational Biology groups and up to 25% bought research time for projects requiring bespoke support.

This post is offered at Band D/E, depending on experience and skills. We will ideally prefer to employ at the most senior level (Band E), but will consider Band D for candidates with less experience showing future promise.

Main duties and responsibility

Core Facility Tasks:

• Data manipulation and visualisation for diverse data modalities (especially sequenc-ing)
• Develop and maintain RNA-Seq and differential expression pipeline(s)
• Design and implement a spatial transcriptomics, single cell RNA-Seq pipeline
• Lead or aid the development of bioinformatics pipelines for omics datasets
• Communicate progress and results within the team and to collaborators
• Provide technical input to grant applications by Institute group leaders
• Lead or assist in the day-to-day running of a compute cluster

Research:

• Freedom to interact with wet-lab scientists producing unique datasets
• Work closely with two new analytics groups: Genomics and Computational Biology
• Help to expand and exploit a versatile set of sequencing capabilities located in high con-tainment, in close collaboration with the Sequencing core facility

Specific requirements

Essential

• A PhD or equivalent in bioinformatics, computer science or relevant discipline
• Experience with high-throughput sequencing data analysis
• Evidence of interacting productively with wet lab scientists
• Knowledge of Unix and Linux operating systems
• Proficiency in R and/or Python programming and versioning tools
• Strong experience in building and deploying distributed pipelines for data science

Desirable

• Experience in working with diverse biological data types (ideally in livestock or immunity)
• Clear understanding of AI and machine learning within computational biology contexts
• Evidence of excellent oral and written communication skills
• Involvement in setting up and/or maintaining computing clusters
• Experience in 10X chromium-generated data analysis
• Ability to work within, but not restricted by, an MS Windows work environment
• A publication record commensurate to the applicant’s career stage

This post is offered at either Band D or Band E (details outlined above), the successful applicant will need to demonstrate existing skills in the field.

To apply for this vacancy please click on the 'Apply' button above.

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