|Location:||Newcastle upon Tyne|
|Funding for:||UK Students, EU Students, International Students|
|Funding amount:||From £18,622 100% Home (UK) tuition fees and an annual stipend at the UKRI rate (2023/24 rate)|
|Placed On:||22nd August 2023|
|Closes:||31st October 2023|
100% Home (UK) tuition fees and an annual stipend at the UKRI rate (£18,622, 2023/24 rate)
Are you interested in learning how to develop novel drug delivery systems with improved bio performance? Our team has been studying how pharmaceutical cocrystals can improve drug solubility and dissolution. Studies can be found here:
Although many studies on cocrystal design are found in the literature, cocrystal formulation development has thus far been marked by a lack of understanding of cocrystal solution chemistry that governs drug supersaturation. The selection of additives remains a largely empirical & time-consuming process. The expected outcome of this research is a conceptual framework for designing cocrystal formulations where a target in vitro drug concentration can be achieved through the rational use of thermodynamic properties and predictions, in combination with drug precipitation kinetics and oral absorption properties.
In this PhD, you will test different additives, such as surfactants, polymers & lipids. You will become an expert on a large number of techniques for physicochemical characterization, such as calorimetric, spectroscopic, and crystallographic, imaging, analytical (HPLC) and pharmaceutical processing. You will also gain in-depth training in equilibrium solubility and in vitro dissolution experiments.
Number of awards: 1
Start date: January 2024
Award duration: The funding covers a 3.5-year PhD.
Dr. Tatiane Machado, School of Pharmacy, Newcastle University
Dr. Oisín Kavanagh, School of Pharmacy, Newcastle University
You must have, or expect to achieve, at least a 2:1 honours degree or international equivalent, in a subject relating to Pharmacy, Pharmaceutical Sciences, Chemistry, or closely related discipline. This studentship is available to both home & international applicants but the funding will only cover the home portion of the fees. Applicants will be responsible for funding the difference. Applicants whose first language is not English require an IELTS score of 6.5 overall with a minimum of 5.5 in each subsection.
How To Apply
To apply for a studentship, you must register and apply by clicking the 'Apply' button, above.
Once registered select ‘Create a Postgraduate Application’.
Use ‘Course Search’ to identify your programme of study:
You will then need to provide the following information in the ‘Further Details’ section:
In addition, before you submit your application you will need to upload the following supporting documentation:
You will not be able to submit your application until you have submitted all required documents/information.
For further details, please contact: Dr Tatiane Machado E-mail: firstname.lastname@example.org
Type / Role: