Research Associate in Liver Cell Biology

Location: Hammersmith Campus 

Job Summary:

A postdoctoral research opportunity is available in the Rashid laboratory, focusing on the investigation of human liver biology and pathology using induced pluripotent stem cell-derived (iPSC) hepatocytes. We invite applications from driven scientists to contribute to our cutting-edge, translational research programme on hepatocyte biology.

Situated at the Hammersmith Campus, the successful candidate will join a collaborative research team investigating both intracellular and extracellular liver cell biology using iPSC-derived hepatocytes in context of cell therapy and disease modelling. The postholder will leverage insights into hepatocyte biology to probe cellular functions and advance the mechanistic understanding of liver pathologies. 

To learn more about Rashid research group, please visit the following link:

https://www.imperial.ac.uk/metabolism-digestion-reproduction/research/digestive-diseases/hepatology--gastroenterology/liver-regeneration-group/

For queries regarding the research opportunities, please contact Dr Tamir Rashid: t.rashid@imperial.ac.uk

Duties and responsibilities:

You will be instrumental in:

• Generation of cutting-edge data to investigate aberrant hepatocyte functions (e.g. protein misfolding)
• Investigation of different liver diseases using multiple disease modelling formats (2D iPSC, organoids, liver-on-chip, ex vivo liver perfusion)
• Investigating transcriptional networks driving hepatocyte development and maturation
• Reporting findings to research sponsors, presenting at conferences, and publishing in peer-reviewed journals.
• Providing guidance to staff and students involved in the project.

Essential requirements:

You should have:

• a PhD in a relevant biomedical discipline, or on track to complete PhD
• Proven experience in multiple research environments with first-authored publications in relevant and refereed journals.
• knowledge of hepatocyte biology
• Experience in cell culture and cell-based assays
• Skillset in dealing with high-dimensional datasets related to cell biology
• experience of leading and managing a research project
• ability to demonstrate a deep knowledge of own research background and to effectively communicate research achievements to a specialist and to a lay audience

Candidates who have not yet been officially awarded their PhD will be appointed as a Research Assistant within the salary range £40,694 - £43,888 per annum.

Further Information: 

This post is based at Imperial’s Hammersmith Campus and it is fixed-term 12 months with a competitive salary, and renewable subject to funding.

Candidates need to complete an online application by submitting their CV.

The on-line interview is TBC.

Should you require any further details on the role please contact: Dr Tamir Rashid (t.rashid@imperial.ac.uk)

The College is a proud signatory to the San-Francisco Declaration on Research Assessment (DORA), which means that in hiring and promotion decisions, we evaluate applicants on the quality of their work, not the journal impact factor where it is published. For more information, see https://www.imperial.ac.uk/research-and-innovation/about-imperial-research/research-evaluation/

The College believes that the use of animals in research is vital to improve human and animal health and welfare. Animals may only be used in research programmes where their use is shown to be necessary for developing new treatments and making medical advances. Imperial is committed to ensuring that, in cases where this research is deemed essential, all animals in the College’s care are treated with full respect, and that all staff involved with this work show due consideration at every level.

http://www.imperial.ac.uk/research-and-innovation/about-imperial-research/research-integrity/animal-research/ 

Imperial College is committed to equality of opportunity, to eliminating discrimination and to creating an inclusive working environment. We are an Athena SWAN Silver award winner, a Stonewall Diversity Champion, a Disability Confident Employer and work in partnership with GIRES to promote respect for trans people.

Closing date: 18/10/2023

To apply, visit www.imperial.ac.uk/jobs and search by the job reference MED04126.

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