Postdoctoral Research Associate

This new full time post is available immediately on a 3 year fixed term basis.

The post

The Faculty of Health and Life Sciences wishes to recruit a Postdoctoral Research Associate to support the work of Prof Steven West. This Wellcome Trust-funded post is available immediately and for three years. The successful applicant will study RNA polymerase II (RNAPII) transcription regulation in human cells. It will focus on the mechanisms of premature transcriptional termination and how these control the expression of genes. The lab has made several interesting and important breakthroughs in this area and the post will build and expand on these. As part of the post, you will receive training/experience in the latest molecular biology methods including CRISPR/Cas9 genome modification, transcriptomic approaches (POINT-seq, mNET-seq, TT-seq, SLAM-seq) and the associated bioinformatic analyses. Specific projects are available to study premature termination pathways that are controlled by ZC3H4 (restrictor) or the Integrator complex. However, candidates are also welcome to come up with their own ideas and will be supported to develop their own projects if they wish to.

About you

We are seeking an enthusiastic person who has either recently obtained their PhD or will soon be completing it or has equivalent qualification/experience in a related field of study. We will consider enthusiastic applicants from any scientific background but expertise in RNA biology, transcription, gene regulation or general Molecular Biology would be an advantage. The post will integrate “wet lab” experiments with the bioinformatic analyses of large datasets. As such, it would be beneficial to have basic experience in bioinformatics and/or coding. As part of the lab, your personal and career development will be strongly supported and you will be joining an environment that prioritises the success of lab members.

Please ensure you read the Job Description and Person Specification for full details of this role.

Further information

For further information please contact Steven West, e-mail s.west@ex.ac.uk or telephone (01392) 727458.

Interviews are expected to take place by mid-November 2023. There is flexibility in terms of the start date.

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