Senior Laboratory Research Scientist

Location: The Francis Crick Institute, Midland Road, London

Short summary

As part of the Human Biology STP the Crick is installing a new automated platform to assist those researchers using stem cell cultures.  The ambition is to largely replace manual propagation of these vital culture systems with automated processes with all of the benefits of reproducibility, quality control and long-term activity that automation affords.  With a large number of research groups already using stem cell culture systems as part of their research, this platform will also provide these groups with an opportunity to optimise and discover new differentiation protocols to improve the quality, reliability and breadth of discovery research at the Crick.  Using your experience of automated liquid handling and laboratory automation you will lead the implementation of this platform, develop best practice for stem cell cultures and maximise the steady state efficiency of the system to deliver the best possible service to researchers.  Lessons learned during this will be disseminated to the wider research community  

Key Responsibilities

These include but not limited to;

• Become the expert in operating and maintaining the liquid handling and automation platform infrastructure and training selected users in its operation.
• Develop optimal protocols, working practices and operational parameters in collaboration with users to maximise benefit to the Crick research community
• Working with stem cell experts and stakeholders to create and optimise protocols for maintenance and passaging of stock cultures and create optimal protocols for stem cell differentiation into specific lineages
• Working with experts from other STP’s to create and implement regular and informative QC regimes
• Creating optimal schedules and working practises to allow for multiple parallel workstreams   

About us

The Francis Crick Institute is a biomedical discovery institute dedicated to understanding the fundamental biology underlying health and disease. Its work is helping to understand why disease develops and to translate discoveries into new ways to prevent, diagnose and treat illnesses such as cancer, heart disease, stroke, infections, and neurodegenerative diseases.

An independent organisation, its founding partners are the Medical Research Council (MRC), Cancer Research UK, Wellcome, UCL (University College London), Imperial College London and King’s College London.

The Crick was formed in 2015, and in 2016 it moved into a new state-of-the-art building in central London which brings together 1500 scientists and support staff working collaboratively across disciplines, making it the biggest biomedical research facility under in one building in Europe.

The Francis Crick Institute will be world-class with a strong national role. Its distinctive vision for excellence includes commitments to collaboration; developing emerging talent and exporting it the rest of the UK; public engagement; and helping turn discoveries into treatments as quickly as possible to improve lives and strengthen the economy. 

• If you are interested in applying for this role, please apply via our website.
• The closing date for applications is 17.10.2023
• All offers of employment are subject to successful security screening and continuous eligibility to work in the United Kingdom.

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