Back to search results

PhD Studentship: Deadly Prostate Cancer in African Men: Are Microbes Involved? Investigating Microbiomes and Human Genomics

University of East Anglia

Qualification Type: PhD
Location: Norwich
Funding amount: £18,622 Competition Funded Project (Home and International)
Hours: Full Time
Placed On: 31st October 2023
Closes: 15th January 2024
Reference: GIHAWIA_U24FMH

Background

With an incidence of >1.4 million cases worldwide, prostate cancer is the most common non-skin cancer in men. Overall, one in eight men will obtain a diagnosis in their lifetime. However, this rate is doubled in men of African descent and tends to be more aggressive.

The reasons for these differences in prostate cancer outcomes across ethnicities are not understood. One possibility is that microbial differences contribute. In groundbreaking research, we have recently found that certain types of bacteria are associated with aggressive prostate cancer. 

In this PhD, you will seek to answer the question: Are differences in prostate cancer outcomes between ethnic groups caused by bacteria? 

Research Methodology

In this PhD, you will refine computational methods for identifying microbes in cancer whole genome sequencing data5. You will apply these to large prostate cancer datasets from men of different ethnic backgrounds collected by the large, collaborative international consortia in which we are involved. You will use bioinformatics and machine learning to explore the microbiome and genomic features of cancer. Ultimately, you will discover important associations that could improve patient care. 

Training

This is a PhD in bioinformatics. During the PhD, you will learn how to deal with "Big Data," high performance computing, pipeline development, and statistical analyses. We have extensive experience helping people to become experts at the forefront of cancer, biology, and data science. A training programme designed specifically for you will be created. You will be a member of UEA’s Cancer Genetics team, an interdisciplinary team comprised of bioinformaticians and lab-based scientists. We have a broad interest in translational cancer molecular studies with the goal of improving patient care including urine-based biomarker development, whole genome sequencing studies, cancer-subtype detection, and bacteria in cancer studies. We will seek Turing award funding to enable the successful applicant to spend part of this studentship in Sydney.

Person specification

A minimum of a 2:1 honour degree in Computer Science, Physics, Mathematics, Engineering, Biological Sciences, Biochemistry, or Biomedical Science. 

This PhD project is in a Faculty of Medicine and Health Sciences competition for funded studentships. These studentships are funded for 3 years and comprise UK (Home) fees, an annual stipend of £18,622 and £1,000 per annum for research training (RTSG). International applicants may apply but are required to secure additional funding to fund the difference between UK and overseas tuition fees (visit: https://www.uea.ac.uk/study/fees-and-funding/fees for details of Home and Overseas fee rates).

Primary Supervisor:

Start Date: October 2024

For more information on this project, please visit https://www.uea.ac.uk/search/courses/

We value your feedback on the quality of our adverts. If you have a comment to make about the overall quality of this advert, or its categorisation then please send us your feedback
Advert information

Type / Role:

Subject Area(s):

Location(s):

PhD tools
 

PhD Alert Created

Job Alert Created

Your PhD alert has been successfully created for this search.

Your job alert has been successfully created for this search.

Ok Ok

PhD Alert Created

Job Alert Created

Your PhD alert has been successfully created for this search.

Your job alert has been successfully created for this search.

Manage your job alerts Manage your job alerts

Account Verification Missing

In order to create multiple job alerts, you must first verify your email address to complete your account creation

Request verification email Request verification email

jobs.ac.uk Account Required

In order to create multiple alerts, you must create a jobs.ac.uk jobseeker account

Create Account Create Account

Alert Creation Failed

Unfortunately, your account is currently blocked. Please login to unblock your account.

Email Address Blocked

We received a delivery failure message when attempting to send you an email and therefore your email address has been blocked. You will not receive job alerts until your email address is unblocked. To do so, please choose from one of the two options below.

Max Alerts Reached

A maximum of 5 Job Alerts can be created against your account. Please remove an existing alert in order to create this new Job Alert

Manage your job alerts Manage your job alerts

Creation Failed

Unfortunately, your alert was not created at this time. Please try again.

Ok Ok

Create PhD Alert

Create Job Alert

When you create this PhD alert we will email you a selection of PhDs matching your criteria.When you create this job alert we will email you a selection of jobs matching your criteria. Our Terms and Conditions and Privacy Policy apply to this service. Any personal data you provide in setting up this alert is processed in accordance with our Privacy Notice

Create PhD Alert

Create Job Alert

When you create this PhD alert we will email you a selection of PhDs matching your criteria.When you create this job alert we will email you a selection of jobs matching your criteria. Our Terms and Conditions and Privacy Policy apply to this service. Any personal data you provide in setting up this alert is processed in accordance with our Privacy Notice

 
 
 
More PhDs from University of East Anglia

Show all PhDs for this organisation …

More PhDs like this
Join in and follow us

Browser Upgrade Recommended

jobs.ac.uk has been optimised for the latest browsers.

For the best user experience, we recommend viewing jobs.ac.uk on one of the following:

Google Chrome Firefox Microsoft Edge