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PhD Studentship: NIHR Exeter BRC PhD Studentship: Understanding the Mechanisms Controlling Beta-cell Disallowed Genes

University of Exeter - Faculty of Health and Life Sciences

Qualification Type: PhD
Location: Exeter
Funding for: EU Students, International Students, Self-funded Students, UK Students
Funding amount: £18,622 The studentship will cover UK tuition fees plus an annual tax-free stipend of £18,622.00 for 3 years full-time, or pro rata for part-time study.
Hours: Full Time
Placed On: 23rd November 2023
Closes: 2nd January 2024
Reference: 5012

Research Theme:

Genetics and Genomics

Programme of Study:

MPhil/PhD Genetics and Genomics, within the Faculty of Health and Life Sciences.

Project description:

This fully-funded PhD studentship will investigate how and why certain genes must be turned-off in insulin secreting pancreatic beta-cells and how failure of gene silencing leads to diseases such as hyperinsulinism. The student will be trained to undertake interdisciplinary work, generating, and analysing their own functional genomic data to study the new disease mechanisms involving disallowed genes. The student will join an interdisciplinary team studying gene regulatory defects in disease (https://owensnick.github.io/) and a world-leading team studying the genetics of hyperinsulinism (https://hyperinsulinismgenes.org/).

NIHR Exeter BRC Commitment:

This Studentship will be nested within the National Institute of Health and Care Research Exeter Biomedical Research Centre (NIHR Exeter BRC), hosted by the Royal Devon University Healthcare NHS Foundation Trust in partnership with the University of Exeter and in collaboration with South West NHS organisations. The first of its kind for the South West peninsula, the Centres fundamental objective is to improve health outcomes for patients and the public by translating scientific breakthroughs into potential new treatments, diagnostics and medical technologies.

This studentship will provide the opportunity to work with world-leading researchers and have access to state-of-the-art facilities. The NIHR Exeter BRC are committed to developing and nurturing a diverse and rich pipeline of talented researchers by equipping them with the knowledge and skills to excel and contribute significantly to the local and national economy via the delivery of high-quality and impactful translational biomedical research. Expertise will be harnessed from across the partnership to deliver the best possible training and career development opportunities, with the student provided the opportunity to be embedded in a rich research culture, with a growing body of early career researchers.

Fees and funding:

For eligible students, the studentship will cover Home tuition fees plus an annual tax-free stipend of at least £18,622 (in alignment with standard Research Council UK rate) for 3 years full-time, or pro rata for part-time study, in addition to a Research Training and Support Grant (RTSG). The student would be based at the Research, Innovation, Learning and Development (RILD) building based at the Royal Devon and Exeter Hospital site in Exeter, near to the St Lukes Campus.

*Students who pay international tuition fees are eligible to apply, but should note that the award will only provide payment for part of the international tuition fee and no stipend. International applicants need to be aware that you will have to cover the cost of your student visa, healthcare surcharge and other costs of moving to the UK to do a PhD.

Timeline:

The closing date for applications is midnight on Tuesday 2nd January 2024.

Interview panels will be held virtually in late January/ early February 2023 for a September 2024 start.

Contact details:

If you would like to discuss the studentships further, please contact the primary supervisor as stated in the advert. If you have any queries surrounding the application process or the BRC more generally, please contact Dr Sophie Gould (NIHR Exeter BRC Training and Events Manager) at S.L.Gould@exeter.ac.uk.

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