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PhD Studentship in From Nature to Industry: Applying H2-metabolising Enzymes to Sustainable Biocatalysis

University of Nottingham - Engineering

Qualification Type: PhD
Location: Nottingham
Funding for: UK Students, EU Students, International Students
Funding amount: £18,622 per annum, for 2023
Hours: Full Time
Placed On: 24th November 2023
Closes: 16th January 2024
Reference: ENG1713

Subject area      (BBSRC Doctoral Training Partnership, Researcher Academy)

UoN Supervisor names  Simone Morra

Applications are invited for a fully funded PhD Studentship at the University of Nottingham in collaboration with HydRegen Ltd.

The project aims at bringing novel robust metalloenzymes into industrial applications that will improve the sustainability of chemical manufacturing.  The main objectives of this PhD project are: 1) to optimise the overproduction of a novel [FeFe]-hydrogenase at high yield and large scale; 2) to apply the enzyme to biocatalytic hydrogenations for the production of high value products.

The student will work in state-of-the-art facilities at the interface between academia and industry and will be trained in fermentation (up 100 L scale), protein overexpression and purification, enzyme immobilisation, and biocatalysis.

Entry requirements: Applicants must have, or should expect to obtain, a 1st class or 2:1 honours degree or a distinction or high merit at MSc level (or international equivalents) in Biotechnology, Biochemistry, Chemistry or related disciplines. Experience in protein expression and purification or biocatalysis (e.g. a placement or a Masters-level research project) will be beneficial.

To make an informal enquiry prior to application, please contact Dr Simone Morra directly (simone.morra@nottingham.ac.uk) with a cover letter and a CV.

Award Start Date            October 2024

Duration of Award          4 years

Terms and Conditions    

Home and international students are welcome to apply for this opportunity. Funding is available for four years from late September 2024. The award covers tuition fee (£4,712) at the home rate plus an annual stipend which was (£18,622) for 2023. This is set by the Research Councils. Please note that successful international candidates will be put forward for a University Fees Difference Scholarship to cover the difference between the home and international fee.

Informal enquiries may be addressed to simone.morra@nottingham.ac.uk or bbdtp@nottingham.ac.uk

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