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Research Assistant/Associate

Newcastle University

Location: Newcastle upon Tyne
Salary: £31,396 to £36,024 per annum.
Hours: Full Time
Contract Type: Fixed-Term/Contract
Placed On: 8th December 2023
Closes: 12th January 2024
Job Ref: 26475

We are a world class research-intensive university. We deliver teaching and learning of the highest quality. We play a leading role in economic, social and cultural development of the North East of England. Attracting and retaining high-calibre people is fundamental to our continued success.

The Role
We are seeking a research assistant (graduate) or research associate (post-doc) to join a vibrant, diverse and supportive laboratory group working at the cutting edge of translational haematopoiesis and immunology research.

You will work on the Wellcome Trust funded project ‘Somatic mutation in human macrophages: defining ontogeny and mechanisms of inflammatory disease'. The aim of the project is to use somatic mutation to map the ontogeny of specialised human macrophage populations during development and to investigate the functional consequences of somatic mutations arising in the bone marrow, on monocyte and macrophage biology.

You will have a strong background in bioinformatics or computation. You will work on data generated by 10X and smartseq-based single cell transcriptomics taking raw or processed data through to analysis using a dedicated remotely accessible workstation with 384GB RAM and 20TB RAID array.

You will have a good working knowledge of R and Python and be able to manipulate and interrogate data presented in range of formats from BAM and FASTQ files to cell count matrices. Experience of single cell analysis pipelines is essential.
Some experience of custom analysis or software design is desirable. Knowledge of good practices regarding a multi-user workstation is also advantageous. You will have a degree in computation, bioinformatics or biology. A PhD is not essential but will be recognised by higher starting salary and pay progression.

The Haematopoiesis and Immunity Lab is focussed on the origin and regulation of immune responses from haematopoiesis in the bone marrow to blood and peripheral tissues. We are funded by MRC, Wellcome Trust, CRUK and other sources. We are a large friendly research group providing a supportive and nurturing environment for top class science.

This is full-time, fixed-term for 18 months available from the 1st of February 2024.

Further information can be obtained by contacting matthew.collin@newcastle.ac.uk.

Find out more about the Faculty of Medical Sciences here.

Find out more about our Research Institutes here.

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