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Postdoctoral Research Vacancy, MRC Protein Phosphorylation and Ubiquitylation Unit

University of Dundee - School of Life Sciences

Location: Dundee
Salary: £36,024 to £41,732 per annum (Grade 7)
Hours: Full Time
Contract Type: Fixed-Term/Contract
Placed On: 31st January 2024
Closes: 29th February 2024

Following an inaugural UKRI Pioneer Award to Sir Philip Cohen, applications are invited for a postdoctoral researcher to fill this position. The project will test the hypothesis that the ubiquitylation of unbranched glucosaccharides formed by errors of metabolism is a mechanism for eliminating these insoluble starch-like molecules before they precipitate in tissues, causing cardiomyopathy, heart failure and other diseases. The initial goal is to detect ubiquitylated unbranched glucosaccharides in cells by exploiting cell lines developed by the lab in which the formation of unbranched glucosaccharides has been accelerated and their elimination suppressed. The longer term goals are to elucidate the mechanism of glycophagy and to identify further examples of sugar ubiquitylation in biology.

Applicants must have a PhD and at least one 1st author paper published or accepted in a peer-reviewed journal. A strong background in biochemistry is essential and experience in one or more of the following is desirable:- protein chemistry, protein ubiquitylation, autophagy; glycogen metabolism. The position will be an opportunity for candidates to broaden their skillset by working in a well-funded lab using state-of-the-art technologies.

For further information about this position please contact Philip Cohen (p.cohen@dundee.ac.uk). To find out more about the MRC Protein Phosphorylation and Ubiquitylation Unit please visit www.ppu.mrc.ac.uk.

The closing date for applications is February 29th 2024. The successful applicant will receive a fixed term contract of one year which can start at any time up to July 1st 2024.

Advantages of location. The MRC Protein Phosphorylation and Ubiquitylation Unit is one of the world’s leading centres for research on protein phosphorylation and ubiquitylation and cell signalling. Dundee has a beautiful location on the estuary of the river Tay. The University is a short walk from the centre of Scotland’s 4th largest city, close to both train and bus stations and a five-minute drive from the airport with twice daily flights to and from London Heathrow. There is affordable accommodation within walkable distance of the lab.

The diversity of our staff and students helps to make the University of Dundee one of the top universities in the UK. Family friendly policies, staff support networks for BME and LGBT staff, membership of Athena Swan and Stonewall, achievement of the Race Equality Charter, as well as a full range of disability services, create an enjoyable and inclusive place to work.

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