|Newcastle upon Tyne
|UK Students, EU Students, International Students
|100% of home fees paid and an annual stipend of £19,887 years 1 and 2, £20,086 year 3
|12th February 2024
|8th March 2024
100% of home fees paid and an annual stipend of £19,887 years 1 and 2, £20,086 year 3. A successful international candidate would be expected to fund the difference in fees.
The project will investigate immortalization, characterization and commercialization of human derived, site specific mucus secreting goblet cells.
That human mucus secreting goblet cells can be developed to produce site specific MUC 2, MUC 5AC and MUC 5B gene products.
Mucus protects absorptive surfaces. In the lung it provides the mucus elevator removing inhaled particulates. Mucus in the small and large intestine primarily comprises the product of the same MUC2 gene, however functionality and structure varies hugely between the two sites.
This PhD will be conducted in collaboration with Newcastle Biobank/NHS, for collection of goblet cells from human biopsies which will be cultured, immortalised and characterised to validate their mucin secreting potential.
The lab has an extensive record in aerodigestive physiology. The student will receive training in relevant techniques, and research skills from an experienced team. Through the supporting spin-out Aelius Biotech, the lab have a strong record of impact through commercialisation.
Number Of Awards: 1
Start Date: 22nd April 2024
Award Duration: The funding covers a three-year PhD
Application Closing Date: 8th March 2024
Sponsor: Aelius Biotech
Professor Jeffrey Pearson - Institute of Biosciences Newcastle University.
Dr Peter Chater - Aelius industrial supervisor
Professor Chris Ward - Translational and Clinical Research Institute Newcastle University
Applicants must have at least a 2.1 honours degree in an appropriate Bioscience related subject, e.g. Physiology, Biochemisty etc.
Applicants whose first language is not English require an IELTS score of 6.5 overall with a minimum of 5.5 in each subsection.
How To Apply
To apply for a studentship, you must register and apply through the University’s Apply to Newcastle Portal
Once registered select ‘Create a Postgraduate Application’.
Use ‘Course Search’ to identify your programme of study:
You will then need to provide the following information in the ‘Further Details’ section:
In addition, before you submit your application you will need to upload the following supporting documentation:
For further details, please contact Professor Jeffery Pearson
Newcastle University Bioscience Institute
Tel 0191208 6996
Type / Role: