Senior Research Associate in Cancer Immunology for Stimulus-Responsive Immune-modulation

Location: Department of Engineering Science, Institute of Biomedical Engineering, Botnar Research Centre, Headington, Oxford 

We are seeking a full-time Senior Research Associate to join an interdisciplinary research team developing new stimulus-responsive techniques for ultrasound-mediated immune-modulation at the Institute of Biomedical Engineering (Botnar Research Centre, Headington).  The full-time post is supported by a benefactor donation to the University and is fixed-term for 24 months, with the possibility of an extension up to 1 year. 

The overall aim of the project is to enable the development and clinical translation of a new generation of protein-based ultrasound-responsive particles specifically designed to illicit immune responses in tumours for enhanced cancer therapy. The specific role of the person appointed will be to design and perform testing both in vitro and in vivo to characterize and optimize the immune-modulatory response elicited by the combination of ultrasound and protein-based particles. 

You should possess a PhD in immunology, cancer biology, biochemistry or relevant discipline, with considerable post-qualification research experience. You also should have the ability to work in a multidisciplinary team of researchers with both physical and life sciences backgrounds engineers, biologists and clinicians, and have strong evidence of research achievement to date.  Experience with a broad range of immunological techniques such as high dimensional flow cytometry, T cell in vitro functional assays, single cell/bulk RNA sequencing and spatial biological imaging is required. An active UK Home Office animal licence is also an essential selection criterion. Additional experience with therapeutic ultrasound, cavitation monitoring, in vivo experimentation and ultrasound-responsive particles will also be viewed favourably.   

Informal enquiries may be addressed to Professor Constantin Coussios (constantin.coussios@eng.ox.ac.uk). 

For more information about working at the Department, see  www.eng.ox.ac.uk/about/work-with-us/. 

Only applications received before midday on 15 April 2024 can be considered. You will be required to upload a covering letter, a brief statement of research interests (describing how past experience and future plans fit with the advertised position), CV and the details of three referees as part of your online application. 

The Department holds an Athena Swan Bronze award, highlighting its commitment to promoting women in Science, Engineering and Technology.

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