Postdoctoral Researcher in Alzheimer's Disease Pathology, Oxford-GSK Institute of Molecular and Computational Medicine

Location: John Radcliffe Hospital, West Wing, Headley Way, Oxford, OX3 9DU. And on occasion, Building of Genomic Medicine, Old Road Campus, Roosevelt Drive, Headington, Oxford, OX3 7BN

We are seeking to appoint a Postdoctoral Researcher in Alzheimer's Disease Pathology to join Professor Laura Parkkinen's research group. This post provides an exciting opportunity to join the newly established multidisciplinary Oxford-GSK Institute of Molecular and Computational Medicine (IMCM) operating within Nuffield Department of Medicine (NDM) in collaboration with Nuffield Department of Clinical Neuroscience (NDCN), Sir William Dunn School of Pathology, Department of Psychiatry and Department of Physiology, Anatomy and Genetics (DPAG).

You will be responsible for creating, establishing, and pursuing appropriate analytical protocols and techniques to support research, particularly in relation to AI-driven algorithms to recognize different hallmark brain pathologies as well as to spatial transcriptomic platforms (i.e. Nanostring GeoMx and 10X Xenium). You will keep meticulous, detailed records of your work and commit to engaging with cloud-based analyses on the IMCM data platform, and will be responsible for the data analysis and interpretation of resultant datasets (with support from core bioinformatics team). This position will also involve preparing manuscripts for publication, contributing ideas for new research projects, developing ideas and preliminary data for generating research income, and presenting detailed research proposals to senior researchers.

It is essential that you hold a relevant PhD/DPhil (or close to completion) in Neuroscience, Molecular Biology, Genetics/Genomics or related area. You will have demonstrable experience in translational human (or animal) neuropathology and knowledge of the brain anatomy and in general molecular biology techniques (immunohistochemistry, microscopy, subcellular fractionation, immunoblotting). A knowledge of neurodegenerative diseases, such as Alzheimer’s Disease, and the ability to manage own research and administrative activities is also essential for this position.

Applications for this vacancy are to be made online and you will be required to upload a supporting statement and CV as part of your online application. Your supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience.

This position is offered full time on a fixed term contract until 30^th September 2027 and is funded by GSK.

Only applications received before 12 midday on Wednesday 26^th June 2024 will be considered. Please quote 173056 on all correspondence.

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