Postdoctoral Scientist - Neurobiology - Dr Anne Bertolotti - LMB 2594

Dr Anne Bertolotti’s pioneering research programme focuses on innovative approaches to boost stress signaling pathways to increase cellular resilience and protect from diverse diseases including neurodegenerative diseases. We have developed approaches to inhibit or activate phosphatases or kinases of the integrated stress response and are progressing towards a structural understanding of these important enzymes (Tsaytler et al., 2011, Science, 332, 91-4; Das et al., 2015, Science, 348, 239-242; Carrara, M., Sigurdardottir, A., & Bertolotti, A. 2017, Nat Struct Mol Biol; Krzyzosiak, A., Sigurdardottir, A. et al., A. 2018, Cell; Szaruga M, et al,. Nat Commun, 2023. 8;14(1):5535; Fatalska A., Hodgson G, et al., Mol Cell. 2024). 

The position is for a Postdoc with expertise in stress signaling, kinases and/or phosphatases, protein biochemistry, enzymology and/or cell-biology. You will be responsible for studying the regulation of kinases and or phosphatases and small molecules activators or inhibitors. 

You will have a PhD in biochemistry or due to complete doctoral studies within 6 months of applying. Relevant experience is required, and this must be best attested by at least one impactful and original publication. 

This is a three-year training and development position suitable for you if you have recently completed your doctoral studies, or you are looking to move into a new research discipline and/or need to further develop your research skills. Working with our world class scientists you will be working in an Institute renowned for its excellent scientific facilities and high-quality research. 

The LMB has a collaborative working culture and state-of-the-art building on the Cambridge Biomedical Campus. We have on-site parking, cycle enclosures and excellent public transport links to the site. We have a staff restaurant with roof terrace and access to a Campus nursery and sports and social facilities. You will be eligible to join our defined benefit pension scheme with an employer contribution of 16%, holiday entitlement of 40.5 days per annum (including bank holidays and privilege days) and a generous employee discount scheme. We are also committed to providing training and development opportunities including support towards role-related qualifications. 

The LMB is a world-class research institute within UK Research and Innovation (UKRI). UKRI is nine research councils, working together across all disciplines and sectors. More information can be found at www.ukri.org and www.mrc-lmb.cam.ac.uk. 

This role qualifies for endorsement by UKRI for a UK Global Talent Visa, for which the successful applicant is likely to be eligible to apply. Immigration costs (visa and health surcharge) can be reclaimed from UKRI after taking up the post (terms and conditions apply). 

To apply and access full details of the vacancy please visit our job board at https://mrc.tal.net/vx/lang-en-GB/appcentre-1/candidate/postings/2889 (via the 'Apply' button above).

If you are unable to apply online, please contact recruit@mrc-lmb.cam.ac.uk. 

Closing date: 01 May 2025

This is a rolling advertisement, and we reserve the right to close or extend this advert, at any time, based on applications received. Therefore, we encourage you to apply at your earliest convenience. Interviews will be held as and when applications are reviewed. 

Final appointments will be subject to a pre-employment screening. 

We actively support equality, diversity and inclusion in all our activities, processes and culture. 

We are a disability inclusive employer and encourage disabled people to apply for this role. You are very welcome to contact us for information about the application process and any adjustments you may require; recruit@mrc-lmb.cam.ac.uk.