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Postdoctoral Research Associate

University of Oxford - Paediatrics

Location: Oxford
Salary: £48,235 to £57,255 per annum (with a discretionary range to £64,228 per annum), Grade 8
Hours: Full Time
Contract Type: Fixed-Term/Contract
Placed On: 16th April 2025
Closes: 29th April 2025
Job Ref: 179212

We are recruiting a highly motivated Postdoctoral Research Associate to join the research group led by Prof Carlo Rinaldi at the University of Oxford. The group explores genetic causes of neurological disorders and aim to develop therapies for such conditions with a high complementary approach, ranging from stem cell modelling to functional genomic.

Enhancers play a pivotal role in governing gene expression, and their disruption is increasingly recognized as a key driver of diseases. This is an exciting opportunity for a postdoctoral scientist to help lead a project focusing on interrogating enhancer function in the context of rare neurological diseases, with the goal to precisely modulate enhancer activity to fine-tune gene expression patterns and offer treatment opportunities for these diseases. The project will use a wide variety of data processing, data analysis, and statistical techniques to functional genomic data (ChIP-seq, RNA-seq, ATAC-seq, co-accessibility). Analysis will be performed on collaborative cloud computing environments using the extensive computing infrastructure developed by the Sanders Lab.

You will be involved with all aspects of the data analysis including design, conduct, and dissemination. You will work at the newly built Institute of Developmental and Regenerative Medicine (IDRM) at the Old Road Campus in the laboratories of Prof Carlo Rinaldi. You will be well supported by the existing joint team, currently consisting of postdocs, bioinformaticians, PhD candidates, and research assistants.

You will be able to receive training in collaborating labs in order to benefit from interaction with researchers in diverse environments. You will be encouraged to attend training and research skill courses provided by the University of Oxford. There will be opportunities for contributing to and leading grant applications if appropriate, as well as being encouraged to submit work for presentation at national and international conferences. In addition, experience gained by supervision and mentoring of junior members in the lab will be useful for career development. The successful applicant will be expected to provide guidance and assistance to other researchers in the group and students, help in the preparation of scientific publications, and represent the group at public engagement events.

This position is offered full-time on a fixed-term contract initially for one year or until 30 September 2026, whichever is sooner, with the possibility to extend provided further external funding is available.

Only online applications received before 12.00 midday on Tuesday 29 April 2025 will be considered. Interviews will be held as soon as possible thereafter. 

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