Research Fellow

The UCL Cancer Institute is the hub for cancer research at University College London (UCL), one of the world's leading universities (www.ucl.ac.uk/cancer). The Institute draws together over 400 talented scientists who are working together to translate research discoveries into better, more effective treatments to improve outcomes for cancer patients. It fosters links between basic cancer researchers across biomedicine and the clinical activities with our associated hospital Trusts, including UCL Hospitals (UCLH) NHS Foundation Trust. Embedded within the UCL Cancer Institute, the CRUK City of London Centre provides essential infrastructure to underpin cancer research within UCL and is a major catalyst in the success of UCL in integrating translational and clinical cancer research with excellent basic science.

About the role

We are looking for a talented and enthusiastic Research Fellow to join the Cell Communication Lab (http://tape-lab.com) at the UCL Cancer Institute.

Using high-throughput single-cell phenoscaping technologies, we have recent uncovered a fundamental stem cell axis in colorectal cancer (CRC) (Qin et al., Cell, 2023) and demonstrated that cancer associated fibroblasts (CAFs) regulate patient-specific drug responses (Ramos Zapatero et al., Cell, 2023). This postdoctoral position will now build on these discoveries to study the role of stem cell plasticity in primary and metastatic CRC.

The primary supervisor will be Prof. Chris Tape, team leader of the Cell Communication laboratory at UCL Cancer Institute (https://www.ucl.ac.uk/medical-sciences/divisions/cancer/our-research/cell-communication-lab and http://tape-lab.com).

The Research Fellow will be supported by core Translational Technology Platform specialists throughout the UCL Cancer Institute (https://www.ucl.ac.uk/medical-sciences/divisions/cancer/translational-technology-platforms).

The post is funded by the UK Medical Research Council until April 2029 in the first instance. The starting salary is contingent on the candidate’s previous experience.

Appointment at Grade 7 is dependent upon having been awarded a PhD; if this is not the case, initial appointment will be at Research Assistant Grade 6B, with payment at Grade 7 being backdated to the date of final submission of the PhD thesis.

Applications should include a CV and a Cover Letter: In the Cover Letter please evidence the essential and desirable criteria in the Person Specification part of the Job Description. (By including a Cover Letter, you can leave blank the 'Why you have applied for this role' field in the application form, which is limited in the number of characters it will allow.)

About you

Successful candidates must have a Postdoctoral qualification (PhD ) or be studying for a PhD in the relevant field.

Experience with 2D and 3D cell culture techniques, including maintenance, optimisation, and high-throughput screening is highly desirable. Experience in wet lab single-cell technologies and high-dimensional computational analysis will be highly advantageous.

Please visit https://www.ucl.ac.uk/work-at-ucl/rewards-and-benefits to find out more.

You can read more about our commitment to Equality, Diversity and Inclusion here https://www.ucl.ac.uk/equality-diversity-inclusion/

Customer advert reference: B02-08837

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