Research Fellow

Salary: Full time starting salary is normally in the range £36,130 to £45,413 with potential progression once in post to £48,149

Contract Type: Fixed Term contract up to November 2027

Job Summary

We are seeking to recruit a Research Fellow at the School of Dentistry, University of Birmingham, with state of the art research facilities, working with Prof. Gabriel Landini and Dr Richard Shelton.

Main Responsibilities

This is a 29 months (ending 30 November 2027) collaborative project between the University of Birmingham and the University of Oxford, funded by the EPSRC aiming to develop understanding of enamel demineralisation to combat human dental caries. Research will be directed towards the following four areas of research:

1) Procuring samples with incipient and artificial caries to be prepared for assessment by conventional high resolution techniques (SRCT, FIB-SEM, AFM, TEM). Prepare and analyse artificial demineralised lesions obtained under various etching conditions with multi-scale match to prototypes.

2) Top-down 4D characterisation of enamel structural evolution using macro- using multiple techniques at macro-, micro- and nano- scale resolution in macro- and micro-fluidics setups to observe enamel etching. Use ‘zoom’ tomography and imaging to resolve structural variation across scales from 30μm down to 3nm to establish a platform for reverse bottom-up enamel remineralisation.

3) Bottom-up multi-modal 4D observation of HAp biological and/or chemical remineralisation. Evaluate enamel demineralisation kinetics in fluidic setups, accelerated/enhanced pathways to enamel-like apatite deposition using biological and mineral means (e.g. chemical precipitation, peptide-driven regeneration and electrophoretic deposition). Use multi-modal, multi-scale 4D microscopy (SEM, AFM, SRCT) for the analysis of the evolution of globule formation, crystal nucleation, self-assembly and growth from ions clusters to polycrystals.

4) Liaise with the collaborators to develop multi-scale, multi-physics reaction-diffusion modelling of HAp dissolution/precipitation to include liquid-solid interaction and evolving environment (pH), transport (specific ion concentrations, dissolution/precipitation conditions) and structure (morphology, size, orientation) of HAp crystallites.

For informal enquires, please contact Prof. G. Landini at G.Landini@bham.ac.uk or Dr. R. Shelton R.M.Shelton@bham.ac.uk 

To download the full job description and details of this position and submit an electronic application online please click on the 'Apply' button above.

Valuing excellence, sustaining investment 

We value diversity and inclusion at the University of Birmingham and welcome applications from all sections of the community and are open to discussions around all forms of flexible working. 

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