Laboratory Research Scientist (LRS)

Location: The Francis Crick Institute, London

Salary: From £36,535 pa with benefits, dependent on skills and experience

About us…  

The Francis Crick Institute is Europe’s largest biomedical research institute under one roof. Our world-class scientists and staff collaborate on vital research to help prevent, diagnose and treat illnesses such as cancer, heart disease, infectious diseases and neurodegenerative conditions. 

To learn more about the Crick, click here.

About the role…  

This is an exciting LRS role which will support two labs: the Heard and the Turner lab. The former focuses on epigenetic processes, including X-chromosome inactivation, in order to learn more about the basic principles of gene regulation, and to explore the roles of chromatin modifications, chromosome organisation and non-coding RNAs on gene expression in development and disease. The Turner lab works on how sex chromosome evolution, and how sex chromosomes regulate germ cell and embryo development, with the principal aim being to develop more personalised disease therapies for men and women. The labs works collaboratively and extensively together and you will need to be a team player to succeed in this role.   

This unique role will ensure that the wider range of operational functions and activities of the labs continues to run smoothly. You will support all scientific programmes in the labs and need exceptional organisational skills as well as experience in next generation sequencing technology and sequencing.   

What you will be doing…  

As an LRS at the Crick, you will:  

• Assisting the Principal Laboratory Research Scientist in general laboratory organisation
• Assisting other lab members with research projects.  
• Providing technical expertise/ input for the development, refinement and troubleshooting of relevant methodologies, in particular in the field of tissue culture, molecular biology (e.g., molecular cloning, generation of transgenic cell lines, genotyping and quantitative PCR). 
• Participating in generation of large-scale datasets using protocols for embryonic stem cell culture, differentiation, next generation sequencing. 
• Coordinating maintenance of mouse colonies with Biological Research Facility at Crick. 
• Organisation and management of the laboratory on the daily basis.    

About you…  

The essential criteria you will bring…  

• BSc in a relevant discipline, or equivalent experience in scientific subject  
• Fundamentals of molecular biology and epigenetics  
• Experience in next generation sequencing methodology and techniques (e.g., RNA-seq, ChIP-seq)  
• Experience in cell culture  
• Excellent organisational skills 

To see the complete job description, click here.  

To learn more about Heard lab here and Turner lab here. 

About Working at the Crick… 

Our values  

• We are bold. We make space for creative, dynamic and imaginative ideas and approaches. We’re not afraid to do things differently. 
• We are open. We’re highly collaborative and interactive, and make sure our activities are visible to the outside world. 
• We are collegial. We show respect for one another, work cooperatively and support the wider community. 

At the Crick we believe that diversity and inclusion are essential to driving innovation and scientific discovery.

We are a Disability Confident employer. Please contact people@crick.ac.uk for assistance.

Read more about our EDI approach here.   

What will you receive?  

We value our team members and offer an extensive range of benefits to support their well-being and development. Find out more here.

Advert information