Bioinformatician/Computational Biologist

About us

The Francis Crick Institute is Europe’s largest biomedical research institute under one roof. Our world-class scientists and staff collaborate on vital research to help prevent, diagnose and treat illnesses such as cancer, heart disease, infectious diseases and neurodegenerative conditions. 

To learn more about the Crick, click here.

About the role 

We are looking for a talented and motivated Bioinformatician to join our group. You will be leading a programme of work related to analysing large biological datasets to identify and solve complex biological problems. You will join the HSC team lead by Prof D Bonnet at the Francis Crick Institute but will also be involved in the overall ERC synergy project involving two other groups, lead by Prof Ilaria Malanchi and Prof Francesca Cicarelli. 

The successful candidate will have a sound understanding of the application of multiomic technologies and bioinformatics in the context of genomics and transcriptomics and practical experience with the processing, analysis and integration of multi-omic data. Collaboration is key to the Crick and therefore the ability to communicate effectively in a multi-disciplinary research environment is essential. 

What you will be doing   

As a Bioinformatician/Computational Biologist at the Crick, some of your key responsibilities will be: 

• Data Analysis:
  • Analysing large biological datasets like DNA sequences, transcriptomics (bulk, scRNAseq) epigenetic profiling (methylome, Atac-Seq, Chip-seq) and proteomics, using computational methods.  
• Algorithm Development:
  • Designing and implementing algorithms to process, analyse, and interpret biological data.  
• Database Management:
  • Developing and maintaining databases for storing and managing biological information.  
• Tool Development:
  • Creating and maintaining bioinformatics tools and software for data analysis and visualisation.  
• Collaboration:
  • Working with biologists, researchers, and other scientists to design experiments, interpret data, and translate findings into biological insights.  
• Communication:
  • Presenting research findings through reports, publications, and presentations. 

See here for more details of research projects currently being undertaken in HSCL lab. 

Please see the full job description here. 

About you  

You will bring 

• Degree in Bioinformatics or Computer Science with a scientific background
• Strong programming skills: Proficiency in languages like Python, R, Java, C/C++ or Perl
• Enjoy working as part of a team
• Experience of statistical methods apply to analysing biological data
• Experience of handling Next Generation sequencing ScRNAseq and ATACseq data

About Working at the Crick

Our values  

• We are bold. We make space for creative, dynamic and imaginative ideas and approaches. We’re not afraid to do things differently. 
• We are open. We’re highly collaborative and interactive, and make sure our activities are visible to the outside world. 
• We are collegial. We show respect for one another, work cooperatively and support the wider community. 

At the Crick, we believe that diversity and inclusion are essential to driving innovation and scientific discovery. If you need assistance with your application, please contact people@crick.ac.uk 

To read more about our EDI approach, click here.   

What will you receive?  

We value our team members and are proud to offer an extensive range of benefits to support their well-being and development. You can find out more about what we offer here.

To apply for this role, please click on the 'Apply' button above.

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