Research Associate in Hydrogen Deuterium Exchange Mass Spectrometry of Membrane Proteins

Job reference: BMH-029573

Salary: £37,694 - £46,049 per annum, depending on relevant experience

Faculty/Organisational Unit: Biology, Medicine Health

Location: Oxford Road

Employment type: Fixed Term

Division/Team: Division of Molecular and Cellular Function

Hours Per Week: 1 FTE

Closing date (DD/MM/YYYY): 03/09/2025

Contract Duration: available from 1 November 2025 for 24 months

School/Directorate: School of Biological Sciences

We are looking for a mass spectrometrist and/or analytical chemist who is self-motivated, highly organised and works as part of a team. The project involves the development of HDX-MS strategies to study the structure and dynamics of bacterial secretesome. In particular, the project will develop the hydrogen deuterium exchange mass spectrometry (HDX-MS) technology to interrogate the conformational dynamics of multi-proteins complexes involved in bacterial translocation and within their native environment.

Essential skills and duties include:

• Hands on experience on HDX-MS of membrane proteins
• Experience in working with robotic systems for HDX workflows
• Excellent technical skills in sample preparation and HDX-MS data analysis
• Extensive and up-to-date theoretical and practical knowledge in working with membrane proteins.
• Extensive experience in working with membrane proteins and developing related methods
• Working with other laboratory members to develop methods and contribute in maintaining equipment
• Writing high-quality research papers.

What you will get in return:

• Fantastic market leading Pension scheme
• Excellent employee health and wellbeing services including an Employee Assistance Programme
• Exceptional starting annual leave entitlement, plus bank holidays
• Additional paid closure over the Christmas period
• Local and national discounts at a range of major retailers

As an equal opportunities employer we welcome applicants from all sections of the community regardless of age, sex, gender (or gender identity), ethnicity, disability, sexual orientation and transgender status. All appointments are made on merit.

Our University is positive about flexible working – you can find out more here

Hybrid working arrangements may be considered.

Please note that we are unable to respond to enquiries, accept CVs or applications from Recruitment Agencies.

Any recruitment enquiries from recruitment agencies should be directed to People.Recruitment@manchester.ac.uk. Any CV’s submitted by a recruitment agency will be considered a gift.

Enquiries about the vacancy, shortlisting and interviews:

Name: Dr Argyris Politis

Email: argyris.politis@manchester.ac.uk

General enquiries:

Email: People.recruitment@manchester.ac.uk

Technical support:

https://jobseekersupport.jobtrain.co.uk/support/home

This vacancy will close for applications at midnight on the closing date.

Please see the link below for the Further Particulars document which contains the person specification criteria.

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