GMP Technician (PERL)

About Us

The PET Centre is part of Guy’s & St Thomas’ NHS Foundation Trust and King’s College London within the School of Biomedical Engineering & Imaging Sciences.

The Positron Emitting Radiopharmaceutical Laboratory (PERL) plays a crucial role in the clinical PET Centre, serving over 8,000 patients and research participants annually from South-East London and beyond. It is an integral part of both King's College London's School of Biomedical Engineering and Imaging Sciences and Guy's & St Thomas' National Health Service (NHS) Foundation Trust. Our PET Center relies heavily on the PERL facility for the supply of radiopharmaceuticals and this is likely to become increasingly important when the new Total Body PET scanner is installed later this year.

Comprising two GMP clean rooms, a QC laboratory, and an R&D laboratory with a total of 24 hot cells, the PERL facility is equipped with a PETtrace high-energy cyclotron and various dispensing units, calibrators, and analysis equipment. It operates under a “Specials” manufacturing license, currently producing [18F]fluorodeoxyglucose (FDG) and [11C]methionine routinely, with ongoing development of additional radiotracers.

About The Role

The role of the GMP Technician is to provide specialist support services to the Positron Emitting Radiopharmaceutical Laboratory (PERL). This facility operates to Good Manufacturing Practice (GMP) standards under a Specials Manufacturing Licence from the Medicines and Healthcare products Regulatory Agency (MHRA). The GMP Technician will be responsible for  performing the Transport of Radioactive Materials, fulfilling 18F-fluoride orders for external customers, and ensure that excellent cleaning standards are maintained, in line with the terms of GMP and the MHRA licence. They will do this by following Standard Operating Procedures (SOPs) and specific instructions given by their manager. This will include observing clean room procedures in relation to handwashing, gowning and clean room behaviour, and making sure that all activities are recorded appropriately. 

The post-holder will become a key support member to the core team responsible for production of radiopharmaceuticals necessary for PET scans used for patient benefit.

This is a full time post (35 hours per week), and you will be offered a fixed term contract for 1 year in the first instance (with possibility of extension).

The usual working hours will be 7 hours per day within the range of 07:00 - 18:30. A****ll work will be done on-site at St Thomas’ Hospital.

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