Research Fellow

About the role

A Research Fellow position is available within the group of Dr Leandro Castellano to undertake and lead a research programme investigating miRNA–mRNA regulatory networks as potential targets for immunotherapy in triple-negative breast cancer. The postholder will be expected to design and deliver independent experimental studies, generating robust and high-quality data to support peer-reviewed publications, future funding applications, and dissemination at both internal seminars and national and international scientific meetings.

In addition to research activities, the role will include the supervision of undergraduate and postgraduate project students, as well as contributions to the wider academic activities of the School, including teaching, public engagement, and the development of a supportive research culture.

The successful candidate will be embedded within a highly collaborative environment, with access to the Sussex RNA Research Centre and the Sussex Cancer Research Centre, providing opportunities to engage with a broad network of researchers working across RNA biology, cancer biology, and cancer immunology.

About you

The successful candidate will have a strong background in molecular biology, with an interest in cancer biology and immunology. You will contribute to the application of advanced molecular and cellular approaches to identify and characterise novel miRNAs involved in tumour immune evasion.

The project will involve the use of CRISPR-based genome editing, the culture and manipulation of cancer cell lines, and a range of in vitro and in vivo experimental techniques. These include, but are not limited to, flow cytometry, immunoblotting, RT–qPCR, and RNA immunoprecipitation. Experience with, or willingness to develop expertise in, these methodologies will be essential.

You should be able to work both independently and collaboratively, demonstrating strong organisational and problem-solving skills, as well as the ability to generate high-quality, reproducible data. Prior experience in RNA biology, cancer research, or immunological assays would be advantageous. A proactive approach to research, together with good communication skills, will be important for contributing effectively to the wider research environment.
About our School

Please find further information regarding the School of Life Sciences on our website.
The School of Life Sciences is proud to hold a Silver Athena Swan Award.

Why work here

Find out more about our reward and benefits package.

Find out about our equality, diversity and inclusion

Further Key Information

Please contact Dr Leandro Castellano (l.castellano@sussex.ac.uk) for informal enquiries.
The University of Sussex values the diversity of its staff and students, and we welcome applicants from all backgrounds.

Eligibility

Visa Sponsorship Queries: This role has been assigned an eligible SOC code and meets the salary requirements for Skilled Worker Sponsorship if full time and appointed at Grade 7.4. Please consult our Skilled Worker Visa information page for further information about Visa Sponsorship.

Please note that this position may be subject to ATAS clearance if you require visa sponsorship.

The University requires that work undertaken for the University is performed in the UK.

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