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Senior Trials Manager

University of Southampton - Southampton Clinical Trials Unit

Location: Southampton
Salary: £46,049 to £58,225 per annum
Hours: Full Time
Contract Type: Fixed-Term/Contract
Placed On: 12th May 2026
Closes: 2nd June 2026
Job Ref: 3404326CM
 

An exciting opportunity for someone with previous clinical trials experience to join the Southampton Clinical Trials Unit (SCTU), within the University of Southampton, in an important role as Senior Trials Manager (STM) within the Early Diagnosis and Translational Group. 

SCTU is a leading UK academic CTU located within the state-of-the-art Centre for Cancer Immunology building at Southampton General Hospital. Southampton Clinical Trials Unit (SCTU) | University of Southampton

SCTU is a UKCRC registered CTU and is core-funded by Cancer Research UK (CRUK) together with funding from the National Institute for Health and Care Research (NIHR) via the Biomedical Research Centre (BRC) and Research Support Service (RSS). 

SCTU has expertise in the design, conduct and publication of clinical trials and other well-designed studies from first-in-human phase I to practice changing phase III trials to large early diagnosis observational studies with rich translational data. Managing a growing portfolio (75% cancer, 25% non-cancer) that covers the complete spectrum of clinical practice, from primary care through to tertiary referral medicine, including pan-cancer experimental therapeutics, surgery, radiotherapy and early diagnosis. Undertaking multi-centre early and late phase clinical trials, we work nationally and internationally to create the evidence for patient benefit that will directly influence routine clinical practice in the NHS and overseas. 

As part of the CRUK and NIHR infrastructure we have close working relationships with our partners, including the Southampton Experimental Cancer Research Centre, NIHR BRC & RSS, University Hospital Southampton, the Centre for Cancer Immunology discovery community and CRUK Centres and Institutes across the UK, with an increasing number of international collaborations. 

The Senior Trials Manager will lead the relevant portfolio team to ensure effective delivery of the overall strategy and delivery priorities for SCTU. This will include resource management, oversight of financial management, new trial development, grant applications, and the ability to anticipate and consider potential issues or opportunities which could affect delivery and growth of the relevant portfolio.

The appointed person must have proven experience of running clinical trials, with a focus on multistakeholder studies collecting patient samples for analysis, and including new trial development.

This position is full time fixed term for 24 months. 

The employing organisation is the University of Southampton which offers a competitive salary, pension scheme, generous holiday entitlement and other benefits. 

For informal queries please contact Nicole Keyworth, Portfolio Lead, on n.e.keyworth@soton.ac.uk

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