MRC Postdoctoral Research Scientist

About us

The MRC Laboratory of Medical Sciences (LMS) is a leading institute for discovery science, focused on the fundamental biology that drives health and disease. Based in London and closely linked to Imperial College London, LMS offers a collaborative, interdisciplinary environment with strengths in epigenetics, developmental biology, and quantitative approaches. Our researchers are supported by cutting-edge facilities and a strong commitment to scientific training and career development. 

About the role

Endocrine-disrupting chemicals (EDCs) are substances, both synthetic and natural, that interfere with hormonal systems, harming organisms and ecosystems. Once in the soil, EDCs persist, bioaccumulate, and disrupt ecosystems, damaging organisms that play vital roles in soil health but little is known about the role of microbes in their bioavailability. The Host-Microbe Co-Metabolism group is tackling this challenge by developing novel high-throughput technologies for the fast identification of EDC-microbe interaction. Our multidisciplinary approach integrates genome engineering, invertebrate and vertebrate models of toxicity, quantitative high-throughput phenotyping and omics approaches. These systems support quantitative and mechanistic studies, allowing us to address questions across kingdoms (Pryor et al., Cell, 2019, Martinez et al 2025 Cell Systems). The ideal candidate will be highly motivated to develop new tools and methodologies to uncover regulatory principles of EDC action on the holobiont. The role offers opportunities to pursue independent research ideas within the lab’s core focus, with strong support for career development and scientific training. 

About you

We’re seeking a highly motivated and independent postdoctoral scientist with a strong proven background in molecular biology and organismal biology (C. elegans/mouse) to develop new genetic tools and methodologies, to dissect and capture EDC function at scale and how they impact invertebrate and mammalian physiology. The role offers opportunities to pursue independent research ideas within the lab’s core focus, with strong support for career development and scientific training. We welcome applicants eager to join and contribute to a collaborative and multidisciplinary team environment. 

What we offer

As well as the exciting opportunities this role presents, we also offer defined benefit pension scheme and excellent holiday entitlement (30 days plus 2.5 privilege days & 8 bank holidays), family friendly policies (6 months full pay maternity & adoption leave), a range of shopping/travel discounts, access to our Employee Assistant Programme Scheme, Health and Wellbeing Support and a salary sacrifice cycle to work scheme.  Please follow this link to find out more - Benefits 

How to apply

For full details of the post and to complete an online application, please click on the 'Apply' button above and upload your CV, names and contacts of two scientific references along with a cover letter stating why you are applying for this role (providing evidence against the requirements of the job as per the job description and person specification). Applications without a cover letter will not be accepted. Please quote reference number LMS 2322 

The final appointment will be subject to pre-employment screening 

Please note that applications may be reviewed by both LMS and Imperial staff 

*Additional allowances comprise a £1,000 lump sum Settlement Allowance plus a yearly Training Allowance of £850 in the first year, paid in monthly instalments. The Training Allowance increases to £1,300 in year two, and £1,800 in year three. 

Closing date: 14 June 2026