Research Technician (0.8 FTE)

Further Information about the UCL Cancer Institute can be found on our website https://www.ucl.ac.uk/cancer/.

The Pillay Laboratory focuses on understanding the molecular and cellular basis of sarcomas, with a particular emphasis on chromosomal instability, tumour evolution and the tumour microenvironment. The group integrates molecular pathology, genomics, and spatial biology approaches to study patient-derived samples and develop clinically relevant insights.

Research in the laboratory combines next-generation and long-read sequencing technologies, spatial transcriptomics, and functional assays in cell models to identify biomarkers and therapeutic vulnerabilities. The work is highly translational, involving close collaboration with clinical partners, biobanks and international research groups to improve diagnostic strategies and patient outcomes in sarcoma.

The postholder will provide specialist technical support to deliver a portfolio of translational sarcoma research projects integrating molecular pathology, genomics and cellular biology. The role will involve the processing and analysis of human tissue samples, execution of sequencing and spatial omics workflows, and support of wet-lab experimental systems including cell culture and flow cytometry.

The postholder will play a key role in ensuring high-quality sample preparation, data generation and laboratory operations, while supporting the development of innovative methodologies to investigate chromosomal instability and tumour biology in sarcoma.

The role is offered on a part-time basis at 0.8 FTE, with flexibility in working pattern agreed with the successful candidate.

Applications should include a CV and a Cover Letter: In the Cover Letter please provide evidence of the essential and desirable criteria in the Person Specification part of the Job Description. (By including a Cover Letter, you can leave blank the 'Why you have applied for this role' field in the application form, which is limited in the number of characters it will allow.)

This role does not meet the eligibility requirements for a Skilled Worker Visa certificate of sponsorship under UK Visas and Immigration legislation. Therefore, UCL will not be able to sponsor individuals who require right to work in the UK to carry out this role.

Interviews will be held on-site at the beginning of July.

Successful candidates must have a Master's degree in molecular biology, genetics, or a related subject, or a histology qualification (e.g., biomedical science) that includes a significant genetic component.

Experience in tissue sample preparation and processing into paraffin wax or frozen blocks, and in cryo-sectioning of frozen samples and microtomy of paraffin blocks across a wide variety of tissues, is essential for the role.

Experience in developing new methodologies & technologies; experience with molecular biology techniques such as Western blotting and flow cytometry; a background in Cancer Biology; and experience in biochemical and cell-based assays are desirable but not essential.

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