Research Assistant (Fixed Term), Renal Organoids, Cambridge-GSK Translational Immunology Collaboration (CG-TIC)

We are seeking a talented research assistant to build and optimise human iPSC-derived renal organoids, using them as a platform to decode the molecular mechanisms behind chronic kidney disease (CKD). This exciting translational role sits at the intersection of innovative stem cell engineering and disease modelling, targeting genetic, metabolic, and immune-driven pathologies. You will utilise proven kidney organoid frameworks to simulate disease states via targeted perturbations, including genetic variants, metabolic stress, and inflammatory cues, and map out downstream phenotypes using a broad suite of laboratory techniques.

The research forms part of the Cambridge-GSK Translational Immunology Collaboration (CG-TIC). This is a major five-year partnership between the University of Cambridge and GSK. CG-TIC is focused on advancing understanding and treatment of immune-mediated kidney and respiratory diseases and leverages the world class capabilities of Cambridge University to provide transformational impact for patients, while aligning with GSK R&D strategic priorities.

Who you'll be working with:

The role is based in the Department of Medicine, working in the lab of Prof. David Thomas within the Cambridge Institute of Therapeutic Immunology & Infectious Disease (CITIID). You will also spend time in the research group of Prof. Katja Röper (Department of Physiology, Development and Neuroscience). You will work across both groups, as well as interacting with GSK partners.

What experience you will have:

With a degree (MSc) in a relevant scientific discipline (e.g., molecular biology, biomedical sciences) and significant laboratory experience, the role requires strong practical skills in sterile cell culture. Experience with CRISPR-Cas9 gene editing and/or organoid systems is highly desirable but not essential, as full training will be provided. You will work in a supportive, collaborative environment with access to state-of-the-art facilities on the Cambridge Biomedical Campus and University Downing site. The position may be particularly suitable for candidates with a strong interest in pursuing a PhD, with potential scope to develop the project and role towards doctoral research training.

We support flexible and family-friendly working and are open to non-standard working patterns. While this is advertised as a full-time role, we would consider applications from candidates who are looking to work less than full-time hours and are open to applicants who live outside Cambridge but are willing to travel to Cambridge when required.

Informal enquiries regarding this position are strongly encouraged: Contact Prof. David Thomas (tdct2@cam.ac.uk) and/or Prof. Katja Röper (kr250@cam.ac.uk).

Fixed term: The funds for this position are available until 10^th October 2029.

We welcome applications from individuals who wish to be considered for part-time working or other flexible working arrangements.

To apply online for this vacancy and to view further information about the role, please visit: www.jobs.cam.ac.uk/job/56326.

Please ensure that you upload a covering letter and a CV in the Upload section of the online application. The covering letter should outline how you match the criteria for the post and why you are applying for this role. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application.

Please include details of your referees, including email address and phone number, one of which must be your most recent line manager.

The interview date for the role is to be confirmed

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

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