(Senior) Clinical Trials Manager

Early application is encouraged as applications will be reviewed on a rolling basis

About the company

Healthcare systems globally are facing significant pressures, and epilepsy is a case-study of those challenges. More than 630,000 people in the UK live with the condition. Over 70% of routine EEGs are clinically inconclusive, and the average time to diagnosis is longer than a year. That leaves people waiting, and clinicians deciding without the evidence they need.   

We built BioEP to close that gap. It analyses background activity in a routine EEG using eight predefined features drawn from peer-reviewed computational neuroscience, returning an objective rating in under five minutes. It works when nothing abnormal is visible, so it supports a decision precisely where conventional reading runs out. Our method is deterministic and explainable, not a black box or deep learning tool.   

BioEP is UKCA-marked and has been validated across 15 NHS sites and more than 6,000 recordings. In June 2026 we raised £3M, co-led by Empirical Ventures and The FSE Group. That investment takes us through our FDA submission this year, extends BioEP into paediatrics and prognosis, and funds research on our next indication: traumatic brain injury.  This role is a unique opportunity to contribute meaningfully to all of these areas.

Founded in 2018 Neuronostics has grown rapidly in the years since. In 2024 our international potential was recognised when we won the Epilepsy Foundation of the USA Shark Tank competition and with it a $125K prize. We've established transformative partnerships with leading industry players: Stratus Neuro (the leading US EEG services provider with 600+ hospital systems), Nervus (UK EEG services), and Neuroelectrics (advanced EEG hardware), creating immediate distribution channels and market access.   

About the role

You will lead the day-to-day delivery of assigned studies within a programme that spans diagnosis, prognosis and paediatrics in the UK, with US studies in preparation. That covers site set-up, ethics and regulatory submissions, monitoring visits, data quality and an inspection-ready trial master file. You will line manage our Clinical Trial Co-ordinators and help shape the processes and templates that our clinical operations run on. We are looking for proven multisite trial management from initiation to close-out, a high standard of Good Clinical Practice, and sound judgement about when to escalate. For consideration at the senior level, you will have strong evidence of sustained delivery across multiple successful studies. 

In this role you will:

The following is a list of the main tasks this job role will handle, but is by no means an exhaustive list and may be varied from time to time:- 

• Lead the day-to-day management of assigned clinical trials, acting as the primary point of contact for the studies managed. 
• Set up clinical sites, prepare ethics committee and regulatory submissions, and ensure that staff at participating sites understand and are able to comply with the protocol. 
• Ensure that trials are undertaken according to Good Clinical Practice, applicable regulatory requirements, ethics approvals, study protocols and company SOPs. 
• Develop and maintain study plans, monitoring plans, study trackers, study manuals, training materials and other study documentation as required. 
• Monitor progress of each site and take appropriate action to support recruitment, protocol compliance, data quality and timely data collection. 
• Maintain trial files, including the trial master file, and oversee the management and quality of site files. 
• Travel to trial sites to carry out initiation visits, monitoring visits, training visits and close-out visits. 
• Identify, assess and address risks or issues that arise during trials, escalating matters appropriately to maintain trial integrity and delivery. 
• Prepare clear progress reports for senior management, including recruitment status, site performance, monitoring findings, data quality, operational risks and decisions required. 
• Line manage and mentor team members. This will include the setting of clear expectations, support their development, reviewing work quality, helping prioritise workload and ensure clear escalation routes. 
• Support the development of clinical operations processes, templates and working practices to improve consistency, quality and efficiency across studies. 
• Work with regulatory, commercial, R&D and technical colleagues to ensure that clinical trial planning and delivery support wider evidence-generation and business needs. 
• Contribute strategic input into future study planning, real-world evaluations and clinical evidence plans. 
• Make recommendations to the leadership team where trial delivery, site experience or clinical evidence requirements need senior input. 
• Identify and scale-up as appropriate where specialist, senior or external support is required, including for international studies, FDA-facing work or complex regulatory matters. 

About you 

Essential: 

• Proven experience in managing complex multi-site clinical trials from initiation to close-out.  
• Proven experience of conducting central and on-site site initiation visits and monitoring visits.  
• Knowledge of UK Clinical research structures, regulatory and ethical systems, and experience of working to a high standard of Good Clinical Practice. 
• Evidence of effective organisational skills including the ability to prioritise workload and be adaptable to changing priorities. 
• Ability to organise staff, management committees and steering committees. 
• Experience of co-ordinating Research Ethics Committees (REC), regulatory authority and local R&D submissions and approvals. 
• Ability to prepare clear reports for senior management on trial progress, risks, site performance and data quality. 
• Ability to work effectively with colleagues across clinical operations, regulatory, commercial, R&D and technical teams. 
• Ability to make sound judgements, take ownership of agreed responsibilities and know when to escalate matters for senior input. 
• Excellent project management skills and teamwork. 
• Excellent verbal and written communication skills. 
• Willingness to travel to undertake monitoring visits. 

Desirable:  

• Experience in managing budgets and financial oversight for clinical trial activities. 
• Experience with preparing for and managing external audits or inspections by regulatory authorities or sponsors.  
• Knowledge or experience in therapeutic areas such as neurology, epilepsy or the development and implementation of medical devices in clinical trials.  
• Experience of supporting real-world evaluations, observational studies or post-market evidence generation. 
• Experience of working with patient advocacy groups to improve trial recruitment and outcomes, including PPI for ethics submissions. 
• Experience contributing to clinical study reports, close-out documentation or regulatory submission materials. 
• Experience of international clinical study operations, including US study conduct or FDA-facing evidence generation requirements. 
• Experience developing or improving clinical operations templates, trackers, standard operating procedures or working practices. 
• Relevant professional training or certification, such as GCP, ACRP, SOCRA or equivalent clinical research training.  

What we can offer

• A role with genuine scope to shape a growing digital MedTech company and its products.   
• A flexible working model that lets you work when you are most productive.   
• A salary set according to experience, plus a performance bonus and the potential for share options.   
• Company pension scheme: you contribute 2% and the company 7% on qualifying earnings.   
• 25 days annual leave, plus public and bank holidays, plus an extra day off for your birthday.   
• A collaborative environment where curiosity and initiative are encouraged and rewarded.   
• A team combining scientific, clinical, technical and commercial expertise.   
• Access to ongoing professional development.   
• Regular staff events and company away days.     

We work a hybrid model, blending time in the office with time at home. We expect regular time together in Bristol: a minimum of two days per week (with more desirable). We are based at Science Creates, a stone’s throw from Bristol Temple Meads Station.    

How to apply

We would encourage you to get in touch early for an informal conversation about any of these roles. Contact recruitment@neuronostics.com to arrange this.   

When you are ready to apply, send a CV and a covering letter setting out how your skills, experience and career plans fit what we are looking for, via the 'Apply' button above (E: recruitment@neuronostics.com).   

Applications will be considered on a rolling basis until the position is filled.