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Postdoctoral Fellow (Papayannopoulos Lab)

The Francis Crick Institute

Location: London
Salary: From £47,500 with benefits, subject to skills & experience
Hours: Full Time
Contract Type: Fixed-Term/Contract
Placed On: 19th August 2026
Closes: 13th September 2026
Job Ref: R2832
 

Location: The Francis Crick Institute, London

Short summary

We are seeking an ambitious Postdoctoral Research Fellow to lead an independent research project investigating how the recognition and processing of PAMPs and DAMPs regulates inflammation and microbial control during fungal and bacterial infections. 

Working within a collaborative and multidisciplinary research environment, you will design and deliver innovative research using molecular, cellular and in vivo approaches, while contributing to high-impact publications, grant applications and the wider research programme. This ERC-funded position offers an excellent opportunity to establish your independent research profile within a world-leading biomedical research institute.

Key Responsibilities 

These include but are not limited to:

  • Leading an independent research project focused on innate immune responses during infection.
  • Designing and carrying out experiments using in vitro systems and mouse models of disease.
  • Applying molecular, cellular and biochemical techniques including flow cytometry, CRISPR, microscopy and transcriptomic analysis.
  • Analysing experimental data and publishing findings in leading scientific journals.
  • Presenting research at national and international conferences.
  • Contributing to grant applications and collaborative research initiatives.
  • Mentoring PhD students and collaborating with researchers across the Crick and external partners. 

About you

You will have: 

  • PhD in immunology, infection biology, biochemistry, cell biology or a related discipline, or be in the final stages of PhD submission.*
  • Strong knowledge of immunology, biochemistry and cell biology.*
  • Experience working with molecular, cellular and mouse models of disease.*
  • Evidence of first-author publications or manuscripts submitted for publication.*
  • Excellent experimental design, scientific writing, organisational and collaborative working skills.*
  • A passion for innovative research and strong drive to publish high-quality science.*

About us

The Francis Crick Institute is a biomedical discovery institute dedicated to understanding the fundamental biology underlying health and disease. Its work is helping to understand why disease develops and to translate discoveries into new ways to prevent, diagnose and treat illnesses such as cancer, heart disease, stroke, infections, and neurodegenerative diseases.

An independent organisation, its founding partners are the Medical Research Council, Cancer Research UK, Wellcome, UCL, Imperial College London and King’s College London.

The Crick was formed in 2015, and in 2016 it moved into a new state-of-the-art building in central London which brings together 1500 scientists and support staff working collaboratively across disciplines, making it the biggest biomedical research facility under one building in Europe.

The Francis Crick Institute will be world-class with a strong national role. Its distinctive vision for excellence includes commitments to collaboration; developing emerging talent and exporting it to the rest of the UK; public engagement; and helping turn discoveries into treatments as quickly as possible to improve lives and strengthen the economy.

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