Engineering Biology PDRA

Full time: 35 hours per week

Fixed term: for 12 months

The Opportunity

We are inviting applications for a Postdoctoral Research Associate to undertake a BBSRC-funded project, delivered as part of the Engineering Biology Hub at Easter Bush, focused on engineering more robust protein expression in chicken through synonymous recoding. The project will apply engineering biology principles to develop more predictable and robust expression systems for avian biotechnology.

This is a collaborative project involving several research groups at the University of Edinburgh, including the Kudla, Gaunt, Grey, McGrew and Glover laboratories. The post will be led by Dr James Glover and based at The Roslin Institute.

By enabling more predictable and robust transgene expression in chicken cells, this work will support the development of improved genetic tools and create opportunities across vaccine research, disease-resilience modelling and egg-based biopharming. The post holder will help plan and deliver experimental work, analyse and interpret data, contribute to the direction of the research, and support the dissemination of research outputs.

What you will be doing

The successful candidate will be responsible for the planning, optimisation and execution of experimental work in engineering biology, molecular biology and avian cell systems, with guidance from the PI and Co-Investigators. This will include techniques such as CRISPR/Cas9 editing, variant library preparation, cell culture, flow cytometry, sequencing-based assays, and quantitative analysis of gene or protein expression (50%).

Analyse and interpret data, ensuring that all data production, recording and documentation are handled with integrity and maintained to a high standard (30%).

Present and discuss research findings within and beyond the research group, and disseminate outputs through contributions to publications, conference presentations, internal reports and follow-on funding applications (10%).

Contribute to wider Engineering Biology Hub activities, including the development of tools and resources, new protocols, collaborative working practices and outreach programmes (10%).

This post is full time, 35 hours per week, and fixed term for 12 months. We are open to considering part-time or flexible working patterns.

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