Biostatistician - Cancer Research (UK) Clinical Trials Unit

Salary: Full time starting salary is normally in the range £36,636 to £46,049 with potential progression once in post to £48,822.

The Cancer Research UK Clinical Trials Unit (CRCTU) is a Department within the School of Medical Sciences at the University of Birmingham. The CRCTU employs a multidisciplinary team of around 200 staff including statisticians, trial management staff, research nurses, monitors, programmers, administrators and IT staff. It specialises in running early and late phase clinical trials in adults and children. Alongside trials portfolios in a broad range of adult solid cancers and haemato-oncology, CRCTU is the national lead for prestigious programmes of children’s cancer and leukaemia trials.  The unit also includes two trials teams dedicated to non-cancer trials: the Diagnostics, Drugs, Devices and Biomarkers team (D3B), running mainly early-phase trials, and the Inflammation, Advanced and Cellular Therapy (I-ACT) team, specialising in trials in rheumatology and advanced therapies.

You will provide statistical expertise and advice on the design, conduct and analysis of Cancer Research UK Clinical Trials Unit’s (CRCTU) clinical trials and allied research. Biostatisticians play a central role in the Unit, actively liaising with clinical investigators, contributing to the design and conduct of clinical trials, being responsible for interim and final analysis of clinical trial data and having a key role in the presentation and publication of results.  As academic members of the University, Biostatisticians contribute to teaching at undergraduate and postgraduate level

Person spec

• Provide statistical advice for the design of clinical trials and related studies, and contribute to protocols and grant applications, under the mentorship of a Senior Biostatistician.
• Determine appropriate analysis of clinical trial data and write statistical analysis plans for trials, under the mentorship of a Senior Biostatistician.
• Undertake appropriate analysis of clinical trial data and prepare reports for Data Monitoring and Steering Committees and contribute to presentations and publications of clinical trial results.
• Collaborate on relevant trial-related projects with researchers in other departments within the University of Birmingham in terms of the provision of statistical advice and/or analysis of data.
• Liaise with Programmers and Trial Coordinators in the setting up of a randomisation process and development of data collections forms and databases for trials.
• Provide statistical analysis to assist Trial Coordinators in the running of trials and monitor data quality of on-going trials. 
• Carry out statistical methodological research relevant to cancer clinical trials and associated translational research in collaboration with senior members of the Biostatistics Team and contribute to presentations and publications of such research.
• Support the delivery of clinical research in accordance with Good Clinical Practice (GCP), the Declaration of Helsinki, applicable legislation (including, but not limited to, the Medicines for Human Use Clinical Trials Regulations, Data Protection Act 1998, Human Tissue Act), the Research Governance Framework for Health and Social Care, Caldicott principals, and applicable NHS Trust and University policies and procedures, (including, but not limited to the University’s Data Protection Policy, Information Security Policy and Code of Practice for Research) in order to protect the research subject and the quality of each study.

Informal enquiries can be made to Aimee Jackson (a.e.jackson@bham.ac.uk) 

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We value diversity and inclusion at the University of Birmingham and welcome applications from all sections of the community and are open to discussions around all forms of flexible working

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