Research Fellow (Trial Manager, Botswana)

The London School of Hygiene & Tropical Medicine (LSHTM) is one of the world’s leading public health universities. Our mission is to improve health and health equity in the UK and worldwide; working in partnership to achieve excellence in public and global health research, education and translation of knowledge into policy and practice.

LSHTM is seeking to appoint a Trial Manager within the Clinical Research Department. The post-holder will be responsible for the day-to-day operational management of ADVANCING-CM, a multi-site phase IIb into phase III randomised clinical trial of adjunctive interferon gamma for HIV-associated cryptococcal meningitis in Botswana, Malawi, South Africa and Uganda. They will work closely with the International Lead Clinician, the experienced senior trial management team and study coordinators at the participating African study sites. The post-holder will be expected to be based full-time at the Trial Coordinating Centre in Gaborone, Botswana for the duration of study recruitment and to travel frequently to the other trial sites. The role will provide operational leadership across trial set-up, regulatory and ethics processes, site initiation and monitoring, trial documentation, data quality, safety-reporting systems and trial governance, ensuring that the study is conducted in accordance with the protocol, Good Clinical Practice (GCP), applicable regulatory requirements and trial procedures.

The successful candidate will have a postgraduate degree, ideally a doctoral degree, in a relevant topic, relevant experience of working on multicentre phase III clinical trials, including Clinical Trials of Investigational Medicinal Products (CTIMPs), experience of trial set-up and site initiation, including preparation and maintenance of essential trial documentation, experience of clinical trial monitoring, including identification and follow-up of monitoring findings and protocol deviations. Further particulars are available in the job description.

The post is full-time 35 hours per week, 1.0 FTE and fixed term until 31 December 2030. The post is funded by Coefficient Giving and is available from 01 January 2027.

The salary will be on the LSHTM salary scale, Grade 6 in the range £46,643 - £52,909 per annum pro rata (inclusive of London Weighting). The post will be subject to the LSHTM terms and conditions of service.  Annual leave entitlement is 30 working days per year, pro rata for part time staff. In addition to this there are discretionary “Wellbeing Days”. Membership of the Pension Scheme is available. This post is based in Botswana, hosted by the Botswana Harvard Health Partnership Institute in Gaborone with frequent travels to sites in Malawi, Uganda and South Africa. 

Applications should be made by clicking the 'Apply' button above. Online applications will be accepted by the automated system until 10pm of the closing date. Any queries regarding the application process may be addressed to jobs@lshtm.ac.uk. Please quote reference ITD-CRD-2026-25.

The supporting statement section should set out how your qualifications, experience and training meet each of the selection criteria. Please provide one or more paragraphs addressing each criterion. The supporting statement is an essential part of the selection process and thus a failure to provide this information will mean that the application will not be considered. An answer to any of the criteria such as "Please see attached CV" will not be considered acceptable. 

Please note that if you are shortlisted and are unable to attend on the interview date it may not be possible to offer you an alternative date.

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