Research Fellow in Immunosuppressant Therapeutic Drug Monitoring

Location: Leeds - Main Campus

Working time: 100%

Contract type: Fixed term (to 30^th June 2027 to complete a specific task or time limited work)

Downloads: Candidate Brief (PDF)

Do you have an interest in diagnostics applications? Would you like to be involved in a multidisciplinary project to develop an immunosuppressant therapeutic drug monitoring sensor to provide better patient care?

We are a multidisciplinary team of researchers focusing on the development of in vitro diagnostics assays and devices to deliver better therapeutic drug monitoring (TDM) – this can optimise antibiotic use which will help combat AMR, or ensure accurate dosing can be achieved where therapeutic windows are narrow such as in immunosuppressants – this will significantly improve health outcomes. In therapeutic drug monitoring, drug concentrations are measured in the body and the results used to guide dosing. This is currently being done for immunosuppressants, but using mass spectroscopy which leads to long delays between sample taking and results being available. We have recently developed an assay for the rapid, accurate and cheap measurement of the immunosuppressant tacrolimus, which will enable routine use of therapeutic drug monitoring.

In this role, you will build on our recent advances and will further develop this assay for therapeutic drug monitoring of tacrolimus into a clinically deployable assay.

You will have a PhD in chemistry, chemical biology or related discipline and a strong background in in vitro diagnostics assay development and validation for clinical use.

Please note that this post may be suitable for sponsorship under the Skilled Worker visa route but first-time applicants might need to qualify for salary concessions. For more information, please visit the Government’s Skilled Worker visa page.

For research and academic posts, we will consider eligibility under the Global Talent visa. For more information, please visit the Government’s page, Apply for the Global Talent visa.

What we offer in return

• 26 days holiday plus approx.16 Bank Holidays/days that the University is closed by custom (including Christmas) – That’s 42 days a year!
• Generous pension scheme options plus life assurance
• Health and Wellbeing: Discounted staff membership options at The Edge, our state-of-the-art Campus gym, with a pool, sauna, climbing wall, cycle circuit, and sports halls.
• Personal Development: Access to courses run by our Organisational Development & Professional Learning team.
• Access to on-site childcare, shopping discounts and travel schemes are also available.

And much more!

To explore the post further or for any queries you may have, please contact:

Professor Christoph Wälti, Professor of Bionanotechnology

Tel: +44 (0) 113 343 2023

Email: C.Walti@leeds.ac.uk

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