Research Technician

University of York - Biology Department

You will provide technical support to post-doctoral research staff and principal investigators carrying out research investigating disease resistance in lettuce for the necrotrophic fungal pathogens Sclerotinia sclerotiorum and Botrytis cinerea, identifying beneficial alleles and markers and evaluating the potential of systems biology to enhance breeding of disease resistance in horticultural crops. 

You will assist the postdoctoral fellow in plant pathogen infection studies, quantitative genetic analysis of disease resistance, gene expression profiling, genotyping and transformation of lettuce. Growth and infection of Brassica and tomato will play a minor role in the project. You will have excellent skills in plant growth, pathogen culture and infection assays. Ideally you will also have experience in molecular biology, particularly nucleic acid extraction and analysis. The position requires working as part of a team and being able to present scientific work clearly and precisely.

The project has been running since May 2015 and has recently moved to the University of York. Transcriptome profiling and network analysis, combined with quantitative genetic studies (mapping populations and diversity sets), will identify novel alleles and associated markers for increasing the resistance of lettuce to both B. cinerea and S. sclerotiorum. Specifically we will:

  1. Use network modelling to identify key regulatory genes in lettuce influencing resistance to B. cinerea and S. sclerotiorum.
  2. Generate and screen lettuce populations to map quantitative resistance against both pathogens.
  3. Integrate mapping, expression and sequence data to identify markers for beneficial alleles. 
  4. Assess broad relevance of key regulatory genes and the systems approach in tomato and Brassica.

The project is funded by BBSRC and industrial partners through the Horticulture and Potato Initiative and involves working with Harper Adams University, University of Reading, A. L. Tozer, Freshtime Ltd. and the AHDB Horticulture.

Please send informal queries about the position to Katherine Denby (Katherine.denby@york.ac.uk). The precise arrangement of the half-time working hours is flexible. This is a fixed term contract up to May 2018 at the latest.

Interviews will be held on Monday 12 January 2017.

For further information and to apply on-line, please click on the ‘Apply’ button below.

The University of York is committed to promoting equality and diversity.

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Northern England