Research Fellow in Chemical Biology/Medicinal Chemistry

University of Sussex - School of Life Sciences

We wish to appoint a Research Fellow in Chemical Biology/Medicinal Chemistry on a project funded by EPSRC EP/P026990/1 at Sussex, which carries on from work published in Chem. Sci. 2016, 7, 2322, on designing inhibitors of a bromodomain called PHIP 2 , which is overexpressed in melanoma. The project involves the synthesis of libraries of mainly fragment molecules for biological evaluation and x-ray structural studies by our collaborators Profs F. von Delft, P. Brennan, Diamond/SGC and later with Dr de Semir California for tests in melanoma-derived cells.  Much of the chemistry will involve C-H activation and Pd catalysis see Adv. Synth. Catal. 2016, 358, 98 . Candidates with a PhD in medicinal chemistry or chemical biology are encouraged to apply. For further details on the Spencer group, see http://www.sussex.ac.uk/lifesci/spencerlab/.

The School of Life Sciences is at the forefront of research in the biological sciences in the UK, coming in the top 10 in the REF 2014.

The School is committed to equality and valuing diversity, and currently holds an Athena SWAN Silver Award. Applications are particularly welcomed from women and black and minority ethnic candidates, who are under-represented in academic posts in science and engineering at Sussex. The School of Life Sciences welcomes applications to academic posts from candidates who wish to work part-time or as job-sharers.

The University offers various schemes to provide real benefits to parents, these can be found at http://www.sussex.ac.uk/humanresources/personnel/familyfriendlypolicies

Potential candidates are strongly encouraged to make informal contact with the Subject Chair for Chemistry Prof Wendy Brown; W.A.Brown@sussex.ac.uk or the Head of the School of Life Sciences Professor Laurence Pearl FRS L.Pearl@sussex.ac.uk , before applying.

For full details and how to apply see our vacancies page

The University of Sussex is committed to equality of opportunity

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