Location: | London |
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Salary: | £39,950 to £45,275 subject to skills and experience |
Hours: | Full Time |
Contract Type: | Fixed-Term/Contract |
Placed On: | 15th March 2024 |
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Closes: | 4th April 2024 |
Job Ref: | R1589 |
Location: The Francis Crick Institute, Midland Road, London
Short summary
This position is available in Prof. Dominique Bonnet’s laboratory. The lab works on human normal and leukaemic stem cells and the role of the microenvironment as well as more recently the effect of pre-leukaemic mutation. https://www.crick.ac.uk/research/a-z-researchers/researchers-a-c/dominique-bonnet/
PROJECT SUMMARY
The lab is interested in understanding the regulation of the haematopoietic stem cells (which produce all the mature cells for the entire life of an individual), both in normal development and during leukaemia. We are specifically interested in the extrinsic mechanisms that regulate these cells and how we could intervene in order to eradicate the leukaemic stem cell. The main objective of the present funded project (CRUK early detection primer award) is to work with Dr Hector Huerga Encabo, senior post-doc in the group who will lead this study, in the characterisation of early traits of leukaemia. The aim of the present study is to identify specific immune cell subsets in the peripheral blood of individuals with preleukemic mutations.
Key Responsibilities
About us
The Francis Crick Institute is a biomedical discovery institute dedicated to understanding the fundamental biology underlying health and disease. Its work is helping to understand why disease develops and to translate discoveries into new ways to prevent, diagnose and treat illnesses such as cancer, heart disease, stroke, infections, and neurodegenerative diseases.
An independent organisation, its founding partners are the Medical Research Council (MRC), Cancer Research UK, Wellcome, UCL (University College London), Imperial College London and King’s College London.
The Crick was formed in 2015, and in 2016 it moved into a new state-of-the-art building in central London which brings together 1500 scientists and support staff working collaboratively across disciplines, making it the biggest biomedical research facility under in one building in Europe.
The Francis Crick Institute will be world-class with a strong national role. Its distinctive vision for excellence includes commitments to collaboration; developing emerging talent and exporting it the rest of the UK; public engagement; and helping turn discoveries into treatments as quickly as possible to improve lives and strengthen the economy.
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