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Research Assistant in Synthetic Cell Design and Construction

Imperial College London

Location: London, Hybrid
Salary: £42,438 to £47,646 per annum
Hours: Full Time
Contract Type: Fixed-Term/Contract
Placed On: 14th May 2024
Closes: 5th June 2024
Job Ref: ENG03119
 

Location / Campus: South Kensington Campus - Hybrid 

Job Summary 

The Department of Chemical Engineering is seeking a Research Assistant to work on the design and construction of engineered molecular robots: synthetic cells. The post is funded by the UKRI and associated with a Marie Sklodowska Curie Action Doctoral Network on Synthetic Cells, SigSynCell. As part of this post, you will enrol on a PhD programme under the supervision of Dr Yuval Elani in the Bioinspired Engineering Group and be part of a collaborative research programme conducted by 12 PhD students and 11 Academics across Europe. 

Cells are known to communicate with one another across large distances using extracellular vesicles (exosomes) as chemical messengers. These membrane-bound compartments are released by sender cells in response to environmental cues and are then taken up and processed by receiving cells, leading to a response, for example the activation of a genetic programme. In this project, you will develop the underlying science to replicate this concept in synthetic cells, enabling them to communicate with one another over large distances. The resulting technology will underpin powerful use cases for synthetic cells as new classes of therapeutic and diagnostic agents. We will achieve this by leveraging and building upon existing biomembrane engineering, microfluidics, and chemical biology technologies already established in the Elani group. As a member of the Bioinspired Engineering group, you will be part of a vibrant, inclusive and dynamic multidisciplinary team working at the forefront of biotechnology. You will be embedded in a world-leading engineering biology ecosystem at Imperial and affiliated with fabriCELL and the Imperial for Synthetic Biology, benefiting from all their training, collaboration and enterprise initiatives. 

The expected start date is around October 2024, although there is some flexibility.

You can be of any nationality and must comply with the following mobility rule: you must not have resided or carried out your main activity (work, studies, etc.) in the UK more than 12 months in the 36 months immediately before your recruitment date. You must not have spent more than 12 months in the 36 months immediately before your recruitment in the same appointing organisation.

You will be expected to register for a PhD at Imperial College and meet the requirements for a PhD https://www.imperial.ac.uk/chemical-engineering/courses/postgraduate/phd/

Essential requirements

  • MRes, MSc, or equivalent in chemistry, chemical engineering, materials science, bioengineering or a related discipline, or equivalent research, industrial or commercial experience
  • Practical experience in relevant research areas (membrane biophysics, chemical biology, cell engineering, microfluidics, molecular bioengineering etc)
  • Experience of working in a multidisciplinary and diverse team

Further Information

The contract will run for 36 months. The post is based in the Department of Chemical Engineering at Imperial College London (South Kensington Campus).

Informal enquiries about the post can be made to Dr Yuval Elani at y.elani@imperial.ac.uk

Apply online via the above ‘Apply’ button.

Further information about the post is available in the job description.

Should you have any queries about the application process please contact chemeng.staffing@imperial.ac.uk.

Closing date: Midnight Wednesday 5th June 2024

For technical issues when applying email support.jobs@imperial.ac.uk

Imperial College is committed to equality of opportunity, to eliminating discrimination and to creating an inclusive working environment. We are an Athena SWAN Silver award winner, a Stonewall Diversity Champion, a Disability Confident Employer and work in partnership with GIRES to promote respect for trans people. 

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