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Research Fellow in Synapse Degeneration and Pathology in Alzheimer's disease

University College London - Division of Biosciences - Research Department of Cell and Developmental Biology

Location: London
Salary: £35,328 to £42,701 per annum, inclusive of London Allowance, Grade 7
Hours: Full Time
Contract Type: Fixed-Term/Contract
Placed On: 10th January 2019
Closes: 10th February 2019
Job Ref: 1776049
 

The appointment will be on UCL Grade 7. The salary range will be £35,328 - £42,701 per annum, inclusive of London Allowance.

Applications are invited for a postdoctoral research fellow to study the cellular and molecular mechanisms that regulate synapse degeneration in the mammalian nervous system. Our lab has made significant contributions to our current understanding of the function of Wnt signalling in synapse formation, plasticity and synapse maintenance. The successful applicant will determine how deficiency in Wnt signalling triggers synapse loss and synaptic dysfunction in the adult brain. The project will be under the direction of Professor Patricia Salinas at UCL. The work will involve analyses of synaptic changes in vivo, in brain slices and cultured neurons using state-of-the-art imaging techniques combined with the latest molecular genetic methods and electrophysiology to determine changes in network connectivity.

Some of the main duties and responsibilities of the post are to develop, plan and undertake scientific research under supervision within a specific research project and work as a member of a research team and to design, develop, refine and analyse experiments in order to obtain reliable and publishable data.

The post is funded by the Alzheimer’s Society and it is funded until 28th February 2021.

The successful candidate must have a PhD (or be studying towards it) in relevant subject area. Appointment at Grade 7 is dependent upon having been awarded a PhD; if this is not the case, initial appointment will be at research assistant Grade 6B (salary £30,922-£32,607 per annum) with payment at Grade 7 being backdated to the date of final submission of the PhD thesis.

Successful candidate must have a strong interest in understanding the mechanisms that modulate synaptic plasticity and synapse degeneration. Experience in cellular neuroscience, cell imaging techniques and/or electrophysiology are also essential.

UCL vacancy reference: 1776049

Applicants should apply online. To access further details about the position and how to apply please click on the ‘Apply’ button.

Informal enquiries should be addressed to Professor Patricia Salinas (email: p.salinas@ucl.ac.uk, telephone: 020 7679 4225). For an outline of the lab’s research interests www.ucl.ac.uk/biosciences/departments/cdb/people/patricia-salinas/salinas-lab

If you have any queries regarding the application process please contact Biosciences staffing on biosciences.staffing@ucl.ac.uk quoting the vacancy reference number: 1776049.

Latest time for the submission of applications: 23:59.

Interview Date: TBC

UCL Taking Action for Equality

We will consider applications to work on a part-time, flexible and job share basis wherever possible.

Our department holds an Athena SWAN Bronze award, in recognition of our commitment to advancing gender equality.

   
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