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Postdoctoral Research Assistant in DNA Nanotechnology

University of Oxford - Department of Physics

Location: Oxford
Salary: £32,236 to £39,609 Grade 7, p.a.
Hours: Full Time
Contract Type: Fixed-Term/Contract
Placed On: 5th June 2019
Closes: 19th July 2019
Job Ref: 140989

Department of Physics, Clarendon Laboratory, Parks Road, Oxford

Grade 7: £32,236 - £39,609 p.a.

Applications are invited for a Postdoctoral Research Assistant in DNA Nanotechnology applied to Molecular Additive Manufacture.

We propose to demonstrate a first-generation molecular printer, a prototype system for atomically precise manufacturing that seeks to produce materials and devices with each atom in its designated position. The molecular printer will use externally programmed motion to enable construction by site-specific chemical additions and modifications to a workpiece. We envision first-generation molecular printers implemented as DNA origami frameworks constructed with sub-nanometre precision by self-assembly. These prototypes will be actuated by cycles of DNA strand displacement and will achieve positioning accuracies on the order of one nanometre. They will allow exploration of the potential of molecular additive manufacture, with the aim of initiating a process of technological development which will continue until atomically precise construction becomes a practical manufacturing technology. This project is a collaboration with Professor William Shih, Harvard University.

The successful candidate will develop techniques for the design, construction, and characterisation of synthetic DNA nanomachines capable of molecular additive manufacture with nanometre precision.

Applicants should possess, or be very close to completion a PhD in a relevant research field.

Previous experience in molecular self-assembly and nanostructure fabrication, single-molecule biophysics, molecular engineering or other relevant research field will be an advantage.

Candidates are expected to demonstrate competence in: management of research activities; development of scientific techniques and experimental protocols; use of specialist scientific equipment; contribution of research ideas; testing hypotheses and analysis of data; collaboration on all aspects of research, including preparation of scientific reports, journal articles and presentation of papers and posters.

The postholder will have the opportunity to teach.

Please direct enquiries about the role to Professor Andrew Turberfield ( will be required to upload a brief statement of research interests, CV and details of two referees as part of your online application.

Only applications received before 12.00 midday on 19 July 2019 can be considered.

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