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Postdoctoral Research Scientist (Molecular Immunology)

Babraham Institute

Location: Cambridge
Salary: £30,000 to £34,166 per annum (depending on experience)
Hours: Full Time
Contract Type: Fixed-Term/Contract
Placed On: 21st June 2019
Closes: 29th July 2019

The Babraham Institute is a charity which is world renowned for its research in life sciences to enhance lives and improve wellbeing.

We are seeking a dedicated and enthusiastic Postdoctoral Research Scientist to join the newly established laboratory of Dr Claudia Ribeiro de Almeida within the Lymphocyte Signalling and Development programme at The Babraham Institute. The Ribeiro de Almeida laboratory studies the emerging role of RNA and RNA binding proteins (RBPs) in controlling B lymphocyte development and immunoglobulin gene rearrangements.

We are interested in the mechanisms regulating immunoglobulin gene rearrangements and their potential implications for age-related immune dysfunction. The ideal candidate must have an interest in immunology and hands-on expertise in biochemistry and molecular biology will be considered an asset.

The post-holder will undertake a pivotal position in our current research to investigate the role of RNA helicases in class switch recombination (CSR) at the immunoglobulin heavy-chain locus. This includes employing state-of-the-art genomic and proteomic approaches to identify novel RBPs implicated in CSR, and exploring their molecular function using biochemical and cellular assays. This work may provide new targets to modulate B cell function during vaccination and immune disease, or uncover pathological mechanisms associated with the development of B cell malignancies.

The successful applicant should have a PhD in a biological science or equivalent qualification, and can demonstrate a proven track record in academic research. Experience of molecular biology, cell culture are essential. In addition, experience in mass spectrometry, Next Generation Sequencing methodologies and RNA biology are highly desirable.

Applicants must hold a PhD or have their thesis submitted when commencing the post. Please note that you will be appointed on the starting salary of £30,000 per annum, if you have not yet been awarded your PhD.

This is a limited term appointment with funding for this post expected to be available until 31st March 2022.

For more information on the work of the group, please visit: https://www.babraham.ac.uk/our-research/lymphocyte/claudia-ribeiro-de-almeida

For informal enquires, or to find out specific details about the research, please e-mail Claudia.Ribeiro@babraham.ac.uk.

Closing date for applications is Monday 29th July 2019.

NO AGENCIES PLEASE

The Babraham Institute holds a silver Athena SWAN award and is committed to promoting and developing a culture of excellence, diversity and mutual respect that supports the Institute’s ambitions and attracts highly motivated and talented people. The Babraham Institute is a Disability Confident Employer and has a positive approach to employing disabled people.

   
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