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Research Scientist (Bacterial Microcompartments)

Quadram Institute Bioscience

Location: Norwich
Salary: £32,255 to £39,345 per annum depending on qualifications and experience
Hours: Full Time
Contract Type: Fixed-Term/Contract
Placed On: 8th October 2020
Closes: 4th November 2020
Job Ref: 1003941

Applications are invited for a Research Scientist to join the Laboratory of Prof Martin Warren in the Food Innovation and Health Programme at Quadram Institute Bioscience (QIB), based in Norwich, UK.

Background:

Many bacteria within the human GI-tract microbiota have the ability to produce specialised organelles called bacterial microcompartments (BMCs), which house specific metabolic pathways to enhance the degradation of mucosal-derived substrates.

The role:

The overall aim of this project is to investigate the form and function of BMCs within the human microbiota in both health and disease. BMCs are proteinaceous organelles found in a broad range of bacteria and are particularly prevalent in enteric species. They represent an emerging area of interest as the BMC is able to confer specific catabolic activities on the bacterium to help in the degradation of mucosal-derived metabolites such as propanediol, ethanolamine and choline. Detailed bioinformatics approaches and microbiome analysis indicate that BMCs likely play an important role within the microbiota, providing key advantages to organisms expressing them over non-BMC containing bacteria in terms of handling toxic intermediates and enhancing flux.

The ideal candidate:

We are seeking a Research Scientist with experience in microbiology and/or biochemistry, imaging, synthetic biology and animal-microbe interactions. You should have a PhD or equivalent in Biochemistry, Microbiology or a related discipline. You will have a proven record in scientific writing and demonstrated ability to perform research and develop novel ideas.

Additional information:

Salary on appointment will be within the range £32,255 to £39,345 per annum depending on qualifications and experience.  This is a full-time post for a contract of 5 years.

For further information and details of how to apply, please visit our web site https://jobs.quadram.ac.uk or contact the Human Resources team on 01603 450462 or nbi.recruitment@nbi.ac.uk  quoting reference 1003941.

We are committed to equal opportunities and welcome applications from all sectors of society.  The Institute supports equality of opportunity within the workplace and expects all employees to share and display these values.  To support our commitment, we have a range of family, faith and diversity friendly working arrangements to help all staff achieve excellence in their area of work.

As a Disability Confident employer, we guarantee to offer an interview to all disabled applicants who meet the essential criteria for this vacancy.

About the Quadram Institute:

The Quadram Institute is a new interdisciplinary research institute dedicated to understanding how food and microbes interact to promote health and prevent disease. Its mission is to deliver healthier lives through innovation in gut health, microbiology and food. A partnership between Quadram Institute Bioscience, the University of East Anglia, the Norfolk and Norwich University Hospital and BBSRC, it brings together scientists and clinicians in a state-of-the-art building on the Norwich Research Park. This is one of Europe’s largest centres of life sciences and home of the John Innes Centre and The Earlham Institute. (https://quadram.ac.uk/).

The Quadram Institute Bioscience is a registered charity (No. 1058499) and is an Equal Opportunities Employer.

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